Extended Data Fig. 1: Single particle data processing scheme and refined structures of the Pf80S ribosome. | Nature Structural & Molecular Biology

Extended Data Fig. 1: Single particle data processing scheme and refined structures of the Pf80S ribosome.

From: Integrated structural biology of the native malarial translation machinery and its inhibition by an antimalarial drug

Extended Data Fig. 1

a, Five states were separated as displayed in the pictured classification scheme, using the following masks: small-subunit (yellow) for separating rotated from non-rotated states, P-site (pink) for non-rotated particles, P-site (blue) for rotated particles and A-site (green) for non-rotated particles. b-f, Final post-processed maps of the five Pf80S ribosome states, shown in cross section. Maps are colored as follows: 60S large subunit in light grey, 40S small subunit in dark grey, mRNA in dark orange, and the A-, P-, and E-site tRNAs in green, cyan, and yellow, respectively. g-k, Corresponding cross-sectioned view of each Pf80S map is shown colored according to local resolution, as calculated in RELION.

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