Extended Data Fig. 2: Comparison of computational VEPs with empirical surface expression scores, highlighting NSIAD scores.
From: A small molecule stabilizer rescues the surface expression of nearly all missense variants in a GPCR
a Hexbin plot comparing surface expression with AlphaMissense scores for all missense variants. NSIAD scores are highlighted. b Hexbin plot comparing surface expression with ESM1b scores for all missense variants. NSIAD scores are highlighted. c Hexbin plot comparing surface expression with EVE scores for all missense variants. NSIAD scores are highlighted. d Hexbin plot comparing surface expression with RaSP scores for all missense variants. NSIAD scores are highlighted. e Hexbin plot comparing surface expression with ThermoMPNN scores for all missense variants. NSIAD scores are highlighted.
