Extended Data Fig. 5: Identification of capsid mutations that caused defects in FG phase-partitioning.
From: Nuclear pore passage of the HIV capsid is driven by its unusual surface amino acid composition
The panels a-c provide more detailed quantifications for the partitioning of capsid mutants into the GLFG phase of Fig. 3a-c separately. They are based on larger datasets. Capsid signals at the FG phase surface and in the FG phase center were integrated separately. Numbers are means; bars indicate mean ± s.d.; n = number of quantified FG particles. Statistical significance between each mutant and wild-type was determined using an unpaired Student’s t-test: *P < 0.05, **P < 0.01, *** P < 0.001, **** P < 0.0001, ns: not significant (P ≥ 0.05). See Supplementary Excel file for tabular data, including P values for statistical significance of group differences.
