Extended Data Fig. 8: Examples of epigenetic and transcriptomic dynamics during the conversion of ESCs to 2 CLCs. | Nature Structural & Molecular Biology

Extended Data Fig. 8: Examples of epigenetic and transcriptomic dynamics during the conversion of ESCs to 2 CLCs.

From: Z-DNA formation regulates the totipotent-like state and primes Zscan4-dependent chromatin compartmentalization

Extended Data Fig. 8

(a) Screenshot of Z-DNA motifs, DNA replication initiation zones, Zscan4 peaks, Z-compartment, and the log2 fold change of histone marks, DNA methylation, and RNA transcription signals between 2 CLCs and ESCs across chromosome 4. (b) Same as ‘a’ for chromosome 2.

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