Extended Data Fig. 3: Filtering and distribution of TE-chimeras across GTEx dataset. | Nature Structural & Molecular Biology

Extended Data Fig. 3: Filtering and distribution of TE-chimeras across GTEx dataset.

From: Transposable element–gene chimera cartography, origination and role in enhancing transcriptome plasticity

Extended Data Fig. 3

a, The number of TE-chimeras which meet criteria for exonization at 3 filtering steps compared between current human genome builds GRCh38 either including (blue) or excluding (green) novel long-read-informed references derived from GENCODE V29. b, Modeling analysis of the number of TE-chimeras detected in promoters (y-axis, average of 10 iterations) which are identified based on the number of individuals analyzed in GTEx (x-axis). c, Pie chart showing the distribution of TE-chimeras separated by TE class in GTEx which pass filtering criteria of proactive promoter usage (absolute 1.5 and 15% relative proportion) and robust detection (TPM over 0.1 in at least 20% of the individuals) d, Density graphs showing the relative number of TE-chimeras detected (y-axis) against the number of tissues in which they are detected (x-axis). Plots are separated by the relative expression-TPM, left-to-right) or class of TE exonized (top-to-bottom).

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