Fig. 3
From: High-throughput analysis of the human thymic Vδ1+ T cell receptor repertoire
Thymic TCRγ and TCRδ repertoires are highly polyclonal. (a,b) Graphical representation of the thymic TRG (left) and TRD (right) repertoires. In these Treemap graphs, each square represents a clonotype bearing a unique nucleotide sequence, its area being proportional to relative abundance in the repertoire; and the colours group the clonotypes by TCR chains. (c) Graphical representation of a PB TRD control repertoire. (d–e) Thymic and PB (f) CDR3 length (number of nucleotides) distributions for each TCR chain. (g) Example of CDR3 length distribution of thymic Vδ1 (top) and Vδ2 (bottom) sequences. (h–i) Rarefaction analysis of repertoires from thymic and PB samples. The number of unique clonotypes in a sample are plotted against its size. Solid and dashed lines are diversity estimates computed by interpolating and extrapolating using a multinomial model respectively.
