Online-only Table 2 Physico-chemical characteristics of the nanomaterials included in the collection.

From: Manually curated transcriptomics data collection for toxicogenomic assessment of engineered nanomaterials

Data set ID

citation

doi

Material type

Short name

Mapping to treatment

Composition

Stabiliser

Coating

Crystal phase

Purity (%)

Impurities

Supplier / Manufacturer

Address

Supplier code

Batch or Lot No.

Nominal Diameter (nm)

Nominal length (micron)

Nominal Specific Surface area (m2/g)

Dispersant

TEM diameter (nm)

TEM width (nm) (median)

TEM length (nm) (median)

No. of walls

BET surafce area (m2/g)

DLS Mean Diameter (water) (nm)

PDI

DLS Mean Diameter (Medium) (nm)

PDI

Zeta potential (water) (mV)

Zeta potential (medium) (mV)

Description of dispersion

Endotoxins (EU/mg)

Shape description

Material Specification sheet

GSE112780

Snyder-Talkington et al. 201649

https://doi.org/10.1080/15287394.2016.1159635

Multi-walled carbon nanotubes

MWCNT

MWCNT

Carbon

None

None

Not applicable

>99.9%

0.78% (Na, 0.41%; Fe, 0.32%)

Hodogaya Chemical Company

Tokyo, Japan

MWNT-7

#05072001K28

60-170

1-19

23

PBS + serum

not applicable

49 ± 13.4

3860 ± 1900

20-50

not provided

not provided

not provided

not applicable

N/A

not applicable

not applicable

not provided

<0.022

long, entangled

http://www.oecd.org/officialdocuments/publicdisplaydocumentpdf/?cote=env/jm/mono(2016)20&doclanguage=en

GSE112780

Snyder-Talkington et al. 201649

https://doi.org/10.1080/15287394.2016.1159635

Crocidolite asbestos

Asbestos

crocidolite

Na2(FeIII)2(FeII)3Si8O22(OH2)

None

None

Not applicable

not given

not given

Kalahari Desert

South Africa

not applicable

As per Cheng et al., 1999.

100-550

11.5

17.1

PBS + serum

not applicable

160 – 800

11500 (range: 2000 – 30000)

not applcable

17.1

not provided

not provided

not applicable

N/A

not applicable

not applicable

not provided

<0.022

long, entangled

 

GSE29042

Dymacek & Guo, 201150

https://doi.org/10.1109/BIBM.2011.76

Multi-walled carbon nanotubes

MWCNT

MWCNT

Carbon

No details at all of the material provided in the paper. Acknowledges Dale Porter and Vince Castranova (NIOSH) for histopathology data so likely similar mateiral to Porter et al., 2010 which used MWNT-7)

  

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

long, entangled

          

GSE35193

Bourdon et al. 201251

https://doi.org/10.1093/toxsci/kfs119

Carbon black

CNP

Carbon black (Printex90)

Carbon

None

None

Not applicable

99

N, H

Evonik Degussa GmbH

Germany

Printex90

not provided

14

not applicable

350

Vehicle (0.9% NaCl MilliQ Water + 10% vol/ Acellular BAL)

not provided

not provided

Not applicable

not applcable

295-338

not provided

not provided

2600

1

not provided

not provided

chains of particles

142

spherical

https://www.thecarycompany.com/carbon-black-printex-90-pwd#specifications

GSE41041

Husain et al. 201352

https://doi.org/10.1016/j.taap.2013.03.018

Titanium dioxide

TiO2

nanoTiO2

TiO2

None

Polyalcohol

Rutile

77.68%

Silicon (5.61%), aluminum (2.42%), zirconium (0.86%) and polyalcohol

Kemira

Pori, Finland

UV-Titan L181

not provided

20.6

not applicable

107.7

0.9% NaCl and 10% acellular BAL fluid

Not determined

Not applicable

not applicable

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

   

GSE42066, GSE42067, GSE42068

Tilton et al. 201453

https://doi.org/10.3109/17435390.2013.803624

TiO2 nanobelts

TiO2-NB

TiO2 nanobelt

TiO2

None

None

100% anatase

not given

not given

Synthesized as described in Hamilton et al. 2009

not applicable

not applicable

not provided

60-300

15-30

not given

SEGM with 10% FBS

10

Not applicable

Not applicable

not applicable

17.94

2897 ± 117

not provided

not provided

not provided

−30.3 ± 2.8

−11.6 ± 1.0

not provided

not provided

long, entangled

https://particleandfibretoxicology.biomedcentral.com/articles/10.1186/1743-8977-6-35

GSE42066, GSE42067, GSE42068

Tilton et al. 201453

https://doi.org/10.3109/17435390.2013.803624

MWCNTs

MWCNTs

MWCNT

Carbon

None

None

Not applicable

95

Residual metal catalysts and carbonaceous impurities removed using a microwave-induced controlled method (Chen and Mitra 2008)

Cheap Tubes Inc.

Brattleboro, VT, USA

not provided

not provided

20-30

10-30

110

DMEM with 10% FBS

Not applicable

20-30

5-10

not given

513

858 ± 58

not provided

not provided

not provided

−11.8 ± 1.1

−10.64 ± 1.0

not provided

not provided

long, entangled

https://www.cheaptubes.com/product/multi-walled-carbon-nanotubes-20-30nm/

GSE51186

Ronzani et al. 201454

https://doi.org/10.1093/jac/dku122

Eudragit RL / PVP 3-layer emulsion NPs

Eudragit

Eudragit RL

ethylacrylate and methylmethacrylate

quaternary ammonium groups (0.5-0.8%)

PVP

Not applicable

not given

not given

Evonik Polymers

Darmstadt, Germany

Eudragit® RL PO (MW = 150,000)

Not given

not given

not given

not given

RPMI 1640 +10% FBS

142 ± 60 

Not applicable

Not applicable

Not applicable

not provided

not provided

not provided

185 ± 70

not provided

0.190 ± 0.023

+56 ± 3

somewhat polydisperse

not provided

spherical

https://doi.org/10.1007/s10565-014-9275-4

GSE55286

Poulsen et al. 201555

https://doi.org/10.1016/j.taap.2014.12.011

Multi-walled CNT

CNTSmall (NRCWE-026)

MWCNT (NRCWE-26)

Carbon

None

None

Not applicable

87

Al2O3 (14.97%), Fe2O3 (0.29%), CoO (0.11%)

Nanocyl

Sambreville, Belgium

NC7000 CNT

not provided

11 ± 4.5

0.8 ± 0.1

245.8

2% serum collected from C57BL/6 mice

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

short

 

GSE55286

Poulsen et al. 201555

https://doi.org/10.1016/j.taap.2014.12.011

Multi-walled CNT

CNTLarge

MWCNT (NM-401)

Carbon

None

None

Not applicable

97

P2O5 (0.14%), CO3 (0.08%) and Fe2O3 -0.05%

IO-LE-TECNanomaterials

Supplied by JRC, Ispra

CP-0006-SG

NM-401 (Mitsui-7)

67 ± 26.2

4 ± 0.4

14.6

2% serum collected from C57BL/6 mice

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

long, entangled

 

GSE55349

Bajak et al. 201556

https://doi.org/10.1016/j.toxlet.2014.12.008

Gold nanoparticles

Au-5

Au5

Au

citrate

None

Not applicable

not given

not given

In-house synthesized

JRC

As per Coradeghini et al., 2013; Turkevich et al., 1951).

5

not applicable

not given

DMEM +10% FBS

4.8 ± 1.0

Not applicable

Not applicable

Not applicable

Not applicable

7.5

not given

not provided

not provided

-30

−13.5

Stable dispersion

not provided

spherical

  

GSE55349

Bajak et al. 201556

https://doi.org/10.1016/j.toxlet.2014.12.008

Gold nanoparticles

Au-30

Au30

Au

citrate

None

Not applicable

not given

not given

In-house synthesized

JRC

As per Coradeghini et al., 2013; Turkevich et al., 1951).

30

not applicable

not given

DMEM +10% FBS

32.2 ± 1.0

Not applicable

Not applicable

Not applicable

Not applicable

37.3

not given

not provided

not provided

not provided

−13.5

Stable dispersion

not provided

spherical

  

GSE60799

Halappanavar et al. 201457

https://doi.org/10.1002/em.21936

Titanium dioxide

TiO2NP10.5

nanoTiO2 (NRCWE‐030)

TiO2

None

None

Rutile

98

<1%

NanoAmor

provided via NRCWE

not applicable

NRCWE‐030

10.5

not applicable

139.1

2% serum in water

not provided

not provided

not provided

not applicable

not provided

126 ± 2

0.157

not provided

not provided

not provided

not provided

Stable dispersion

not provided

slighly elongated

Can’t find this size particels for rutile in current listing

GSE60799

Halappanavar et al. 201457

https://doi.org/10.1002/em.21936

Titanium dioxide

TiO2NP38

nanoTiO2 (NRCWE‐025)

TiO2

None

None

Rutile

98

<1%

Nabond

provided via NRCWE

not applicable

NRCWE‐025

38

not applicable

28.2

2% serum in water

not provided

not provided

not provided

not applicable

not provided

214 ± 6

0.172

not provided

not provided

not provided

not provided

Stable dispersion

not provided

spherical

Orignal specifiction sheet not located online

GSE60798

Halappanavar et al. 201457

https://doi.org/10.1002/em.21936

Titanium dioxide

TiO2NP10

nanoTiO2 (NRCWE‐001)

TiO2

None

None

Rutile

98

<1%

NanoAmor

provided via NRCWE

not applicable

NRCWE‐001 (no charge)

10

not applicable

99

2% serum in water

not provided

not provided

not provided

not applicable

not provided

108 ± 1

0.145

not provided

not provided

not provided

not provided

Stable dispersion

not provided

spherical

Can’t find this size particels for rutile in current listing

GSE60798

Halappanavar et al. 201457

https://doi.org/10.1002/em.21936

Titanium dioxide

TiO2NP10+

nanoTiO2 (NRCWE‐002)

TiO2

None

None

Rutile

98

<1%

NanoAmor

provided via NRCWE

not applicable

NRCWE‐002 (Positively charged)

10

not applicable

84

2% serum in water

not provided

not provided

not provided

not applicable

not provided

1719 ± 166

0.362

not provided

not provided

not provided

not provided

Highly agglomerated /Unstable dispersion.

not provided

roughly spherical

 

GSE63552

Nymark et al. 201558

https://doi.org/10.3109/17435390.2015.1017022

MWCNT

MWCNT

MWCNT (Mitsui7)

Carbon

None

None

N/A

>99.9%

Fe, Si, Na, Mg, Ca, O

Mitsui & Co., Ltd.,

Tokyo, Japan

MWCNT-7

not stated

60-170

1-19

23

BEGM with 0.6 mg/ml BSA

not applicable

180

4600

not provided

8.3

not provided

not provided

not provided

not provided

not provided

not provided

rapid sedimentation

not provided

long, entangled

 

GSE63552

Nymark et al. 201558

https://doi.org/10.3109/17435390.2015.1017022

standard reference crocidolite asbestos

crocidolite

crocidolite

Na2(FeIII)2(FeII)3Si8O22(OH2)

None

None

N/A

not given

Si, Al, O, Na, Mg, K, Ca

UICC (Union for International Cancer Control

Geneva Switzerland

not stated

Lot# 05072001K28

not applicable

not applicable

not applicable

BEGM with 0.6 mg/ml BSA

not applicable

1100 ± 500

21000 ±1800

not applicable

1.07

not provided

not provided

not provided

not provided

not provided

not provided

rapid sedimentation

not provided

long, entangled

 

GSE63552

Nymark et al. 201558

https://doi.org/10.3109/17435390.2015.1017022

non-carcinogenic glass wool (Neg Contol)

glass wool

glass wool

SiO2

None

None

N/A

not given

C

Dr David Brown, Heriot Watt University

MMVF10

not stated

 

not applicable

 

BEGM with 0.6 mg/ml BSA

not applicable

74 ± 28

5700 ± 3700

not applicable

22

not provided

not provided

not provided

not provided

not provided

not provided

rapid sedimentation

not provided

long, entangled

  

GSE63806

Pisani et al. 201559

https://doi.org/10.1186/s12864-015-1521-5

Silica

AEROSIL® 200

nanoSiO2

SiO2

None

None

hydrophilic fumed silica

99.8

SiO2

Evonik

Germany

not stated

not stated

12

not applicable

200

DMEM/F12 with 10% FBS

not provided

not provided

not provided

not provided

not provided

10 ± 4

not provided

160 ± 90

not provided

not provided

not provided

not provided

not provided

disks with diameter 10 ± 5 nm and thickness 2 ± 0.3

 

GSE81569

Rahman et al. 201760

https://doi.org/10.1093/mutage/gew048

Anatase TiO2

aTiO28

nanoTiO2 (anatase)

TiO2

None

None

Anatase

not given

Al, Si, Na, P, S, Zr

Sachtleben Chemie GmbH

Germany

Hombikat UV100

Actually got from OECD programme

8

not applicable

> 250

MilliQ water

8

Not applicable

Not applicable

not applicable

234.47–229.00

148.4 ± 38.3

not provided

not provided

not provided

not provided

not provided

not provided

not provided

spherical

http://kuroppe.tagen.tohoku.ac.jp/~dsc/0075e072.pdf

GSE81564

Rahman et al. 201760

https://doi.org/10.1093/mutage/gew048

Anatase TiO2

aTiO220

nanoTiO2 (anatase)

TiO2

None

None

Anatase

99%

none

Cristal Global (http://www.cristal.com)

PC105

Actually got from OECD programme

30

not applicable

 

MilliQ water

~30

~35–70

not provided

not applicable

90

242.9 ± 53.1

not provided

not provided

not provided

not provided

not provided

not provided

not provided

elongated

  

GSE81568

Rahman et al. 201760

https://doi.org/10.1093/mutage/gew048

Anatase TiO2

aTiO2300

nanoTiO2 (anatase)

TiO2

None

None

Anatase

99%

Al, Zr, polyalcohol

Cristal Global (http://www.cristal.com)

tiona

Actually got from OECD programme

300

not applicable

 

MilliQ water

100–120

Not applicable

Not applicable

not applicable

10

130.1 ± 49.8

not provided

not provided

not provided

not provided

not provided

not provided

not provided

spherical

  

GSE81567

Rahman et al. 201760

https://doi.org/10.1093/mutage/gew048

Mixed anatase and rutile TiO2

raTiO2

nanoTiO2 (rutile/anatase mix)

TiO2

None

None

81.5:18.5 Rutile/anatase

99%

none

Evonik Degussa GmbH

Germany

P25

Actually got from OECD programme

22/40

not applicable

 

MilliQ water

18-52

Not applicable

Not applicable

not applicable

52.81–55.49

242.9 ± 56.4

not provided

not provided

not provided

not provided

not provided

not provided

not provided

spherical

 

GSE81565

Rahman et al. 201760

https://doi.org/10.1093/mutage/gew048

Rutile Titanium dioxide with hydrophillic coating

rTiO2 (HY)

nanoTiO2 (rutile hydrophilic)

TiO2

None

Modified Dimethicone (2 wt%)

Rutile

91.3

Al, Si, Fe and S

Sachtleben Chemie GmbH

Germany

UV Titan M262

Actually got from OECD programme

20

not applicable

 

MilliQ water

18-52

Not applicable

Not applicable

not applicable

51.69–50.8

110.1 ± 27.9

not provided

not provided

not provided

not provided

not provided

not provided

not provided

spherical

 

GSE81566

Rahman et al. 201760

https://doi.org/10.1093/mutage/gew048

Rutile Titanium dioxide with hydrophobic coating

rTiO2 (HP)

nanoTiO2 (rutile hydrophobic)

TiO2

None

Modified Glycerol (1-2 wt %)

Rutile

92.7

Al, Si, S

Sachtleben Chemie GmbH

Germany

UV Titan M212

Actually got from OECD programme

21

not applicable

 

MilliQ water

~30

~35–70

not provided

not applicable

57.07–57.18

39.3 ± 7.3

not provided

not provided

not provided

not provided

not provided

not provided

not provided

elongated

 

GSE98236

Pisani et al. 201761

https://doi.org/10.1080/17435390.2017.1378749

Magnetic mesoporous silica

M-MSNs

M-MP-Silica NP (Pristine)

Fe3O4 core and SiO2 shell

None

None

amorphous

not provided

not provided

In-house synthesized as per Nyalosaso et al. (2016)

Not applicable

Not applicable

not provided

not applicable

not given

HBS (20mM Hepes, 5mM NaCl) or 1X PBS at pH 7.4 and 20 °C.

117 ±2

not applicable

not applicable

not applicable

not provided

172 ±6

0.17

not provided

not provided

-39.1 ±1.4

not provided

not provided

not provided

spherical

  

GSE98236

Pisani et al. 201761

https://doi.org/10.1080/17435390.2017.1378749

Magnetic mesoporous silica

M-MSNs

M-MP-Silica NP (PEG)

Fe3O4 core and SiO2 shell

None

PEG

amorphous

not provided

not provided

In-house synthesized as per Nyalosaso et al. (2016)

Not applicable

Not applicable

not provided

not applicable

not given

HBS (20mM Hepes, 5mM NaCl) or 1X PBS at pH 7.4 and 20 °C.

123 ±3

not applicable

not applicable

not applicable

not provided

156 ±1

0.18

not provided

not provided

-30.4 ±2.9

not provided

not provided

not provided

spherical

  

GSE98236

Pisani et al. 201761

https://doi.org/10.1080/17435390.2017.1378749

Magnetic mesoporous silica

M-MSNs

M-MP-Silica NP (DMPC)

Fe3O4 core and SiO2 shell

None

DMPC

amorphous

not provided

not provided

In-house synthesized as per Nyalosaso et al. (2016)

Not applicable

Not applicable

not provided

not applicable

not given

HBS (20mM Hepes, 5mM NaCl) or 1X PBS at pH 7.4 and 20 °C.

132 ± 4

not applicable

not applicable

not applicable

not provided

180 ± 2

0.12

not provided

not provided

-10.3 ± 0.4

not provided

not provided

not provided

spherical

  

GSE122197

Ilves et al. 201962

https://doi.org/10.1186/s12989-019-0309-1

Copper oxide

CuO

CuO

CuO

none

none

monoclinic

99

not provided

PlasmaChem GmbH

Berlin, Germany

NanoSolutions

YF1309121

10-20

not applicable

42 ± 2

Krebs

12.00 ± 0.37

not applicable

not applicable

not applicable

not provided

41 ± 28

not provided

62 ± 50

not provided

14.0 ± 1.2

not provided

not provided

not provided

spherical

 

GSE122197

Ilves et al. 201962

https://doi.org/10.1186/s12989-019-0309-1

Copper oxide

CuO COOH

CuO_COOH

CuO

COOH

none

monoclinic

99

not provided

PlasmaChem GmbH

Berlin, Germany

NanoSolutions

YF140114

10-20

not applicable

7.4 ± 0.5

Krebs

6.45 ± 0.16

not applicable

not applicable

not applicable

not provided

121 ± 91

not provided

128 ± 58

not provided

- 7.3 ± 0.5

not provided

not provided

not provided

spherical

 

GSE122197

Ilves et al. 201962

https://doi.org/10.1186/s12989-019-0309-1

Copper oxide

CuO NH3

CuO_NH3

CuO

NH3

none

monoclinic

99

not provided

PlasmaChem GmbH

Berlin, Germany

NanoSolutions

YF140114

10-20

not applicable

6.1 ± 0.5

Krebs

9.53 ± 0.22

not applicable

not applicable

not applicable

not provided

46 ± 36

not provided

96 ± 75

not provided

27.7 ± 0.5

not provided

not provided

not provided

spherical

 

GSE122197

Ilves et al. 201962

https://doi.org/10.1186/s12989-019-0309-1

Copper oxide

CuO PEG

CuO_PEG

CuO

PEG

none

monoclinic

99

not provided

PlasmaChem GmbH

Berlin, Germany

NanoSolutions

YF140114

10-20

not applicable

not given

Krebs

7.46 ± 0.42

not applicable

not applicable

not applicable

not provided

100 ± 36

not provided

189 ± 113

not provided

- 16.8 ± 0.4

not provided

not provided

not provided

spherical

 

GSE122197

Kooter et al. 201963

https://doi.org/10.1021/acsnano.9b01823

Copper oxide

nCuO

CuO

CuO

none

none

monoclinic

99

not provided

PlasmaChem GmbH

Berlin, Germany

NanoSolutions

not stated

10-20

not applicable

10-2po1ee

Air with 50% relative humidity

not provided

not applicable

not applicable

not applicable

55

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

spherical

 

GSE122197

Kooter et al. 201963

https://doi.org/10.1021/acsnano.9b01823

Copper oxide

nCuOCOOH

CuO_COOH

CuO

COOH

none

monoclinic

99

not provided

PlasmaChem GmbH

Berlin, Germany

NanoSolutions

not stated

10-20

not applicable

10-2po1ee

Air with 50% relative humidity

not provided

not applicable

not applicable

not applicable

55

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

spherical

 

GSE30200

Sellamuthu et al. 201165

https://doi.org/10.3109/08958378.2011.625995

Min-U-Sil-5 crystalline silica

Silica

Silica

SiO2

None

None

Crystalline

not stated

not stated

US Silica

Berkeley Springs, WV

Min-U-Sil-5 c

not stated

not stated

not stated

not stated

Serum-free F-12K

not stated

not stated

not stated

not applicable

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

Endotoxin-free

spherical

 

GSE46998

Søs Poulsen et al. 201366

https://doi.org/10.1371/journal.pone.0080452

Multi-walled carbon nanotubes (MWCNTs)

MWCNTs

MWCNT

Carbon

None

None

N/A

99%

not stated

Hadoga Chemical industry (formerly Mitsui)

MWCNT- XNRI-7 (also called Mitsui7)

05072001K28

100

not applicable

not stated

0.9% NaCl and 10% acellular BAL fluid

74.4 ± 27.2

100

3860 (27.5% of particles > 5000)

not provided

not provided

5000

1

not provided

not provided

not provided

not provided

good

not provided

Tubes: intertwined and agglomerated, with both long and straight, and bendy

slightly skewed unimodal

 

GSE62253

Böhmert et al. 201567

https://doi.org/10.3109/17435390.2014.980760

Silver NPs

AgPURE

NanoAg

Ag

4% Tagat T and 4% Tween 20

None

N/A

not stated

not stated

Rent a Scientist GmbH

Regensburg, Germany

similar to BAM001 and NM-300

not stated

not provided

not applicable

not stated

DMEM + 10% heat inactivated FBS

15

N/A

N/A

not applicable

not provided

28

not provided

not provided

not provided

not provided

not provided

5% Ag release in 24 hours for 5 mg/mL in cell culture medium

not provided

spherical

 

GSE62769

Perkins et al. 201568

https://doi.org/10.1093/hmg/ddu551

crocidolite asbestos fibers

crocidolite asbestos

asbestos

 

none

None

Crocidolite

not stated

not stated

NIEHS reference sample

South Africa

not stated

not stated

not provided

not provided

not stated

Hank’s buffered saline solution (HBSS)

not provided

not provided

not provided

not applicable

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

Tubes

 

GSE62769

Perkins et al. 201568

https://doi.org/10.1093/hmg/ddu551

cristobalite silica particle

cristobalite silica

Silica

SiO2

none

None

Cristobalite

95.5 ± 0.03

not stated

C&E Mineral Corp

King of Prussia, PA, USA

not stated

not stated

2016 ± 200

not applicable

5.1

Hank’s buffered saline solution (HBSS)

not provided

not provided

not provided

not applicable

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

Tubes

 

GSE75429

Rahman et al. 201769

https://doi.org/10.1016/j.mrgentox.2017.08.005

Multi-walled CNT

Mitsui-7

MWCNT (Mitsui7)

Carbon

none

None

N/A

not stated

<1 (Na, Mn, Al, Ni, Mg (Na: 499 ± 103 μg/g, Mg: 1 ± 1 μg/g, Al: 66 ± 19 μg/g, Fe: 355 ± 2 μg/g, Ni: 1 μg/g)

Mitsui’ & Company

Japan

not stated

not stated

40-90

not applicable

24-28

0.05% BSA in water

N/A

74 ± 28

5700 ± 3700

not provided

28

not provided

not provided

682 ± 13

not provided

not provided

not provided

not provided

not provided

Tubes

 

GSE75429

Rahman et al. 201769

https://doi.org/10.1016/j.mrgentox.2017.08.005

Multi-walled CNT

NM-401

MWCNT (NM-401)

Carbon

none

None

N/A

not stated

<5 Na, Mn, Al, Ni, Mg (Na: 581 ± 32 μg/g, Fe: 379 ± 71 μg/g, Mg: 0 ± 0.3 μg/g, Al: 59 ± 4 μg/g, Ni: 2 μg/g)

IO-LE-TEC Nanomaterials (CP-0006-SG)

not stated

not stated

10-30

5-15

40-300

0.05% BSA in water

N/A

67 ± 26.2

4000 ± 2400

not provided

18

not provided

not provided

710 ± 17

not provided

not provided

not provided

not provided

not provided

Tubes

  

GSE16727

Busch et al. 201070

https://doi.org/10.1186/1471-2164-11-65

Tungsten carbide

WC

WC

WC

none

None

N/A

not provided

not provided

In-house produced from powder by chemical process and deaggregated and mixed via ball mill

not stated

not applicable

not applicable

not applicable

RPMI + 5% FBS

not given

not provided

not provided

not applicable

6.9

not provided

not provided

145 ± 5

0.2

-35

-20

stable in culture medium for 1 week

not provided

spherical

   

GSE16727

Busch et al. 201070

https://doi.org/10.1186/1471-2164-11-65

Tungsten carbide cobalt

WC-Co

WC-Co

WC-Co

none

None

N/A

not provided

not provided

In-house produced from powder by chemical process and deaggregated and mixed via ball mill

not stated

not applicable

not applicable

not applicable

RPMI + 5% FBS

not given

not provided

not provided

not applicable

6.6

not provided

not provided

145 ± 5

0.2

-50

-23

stable in culture medium for 1 week

not provided

spherical

   

GSE39330_jurkat

Tuomela et al. 201371

https://doi.org/10.1371/journal.pone.0068415

Zinc oxide

ZnO-1

ZnO

ZnO

none

unknown

N/A

not provided

not provided

IBU-tec advanced materials AG

Weimar, Germany

not stated

12

not applicable

60 ± 5

Sonication in ultra-pure water, prepared immediately before use

14.7 ± 1.07

N/A

N/A

not applicable

not provided

159±3

0.15

153±4

0.12

-23.9±0.2

-17.3±0.1

not provided

not provided

spherical

  

GSE39330_jurkat

Tuomela et al. 201371

https://doi.org/10.1371/journal.pone.0068415

Zinc oxide

ZnO-2

mandelic_acid_ZnO

ZnO

none

mandelic acid

N/A

not provided

not provided

In-house functionalisation of ZnO-1

Not applicable

Not applicable

Not applicable

12

not applicable

60 ± 5

Sonication in ultra-pure water, prepared immediately before use

11.7±0.77

N/A

N/A

not applicable

not provided

312±3

0.1

287±2

0.12

-9.9±0.2

-12.3±0.2

not provided

not provided

spherical

 

GSE39330_jurkat

Tuomela et al. 201371

https://doi.org/10.1371/journal.pone.0068415

Zinc oxide

ZnO-3

mercaptopropyl_trimethoxysilane_ZnO

ZnO

none

mercaptopropyl-trimethoxysilane

N/A

not provided

not provided

In-house functionalisation of ZnO-1

Not applicable

Not applicable

Not applicable

12

not applicable

60 ± 5

Sonication in ultra-pure water, prepared immediately before use

14.6±1.2 (core) 10.9±0.65 (shell)

N/A

N/A

not applicable

not provided

548±4

0.14

341±5

0.14

-23.3±0.4

-23.3±0.4

not provided

not provided

spherical

 

GSE39330_jurkat

Tuomela et al. 201371

https://doi.org/10.1371/journal.pone.0068415

Zinc oxide

ZnO-4

methoxyl_ZnO

ZnO

none

methoxyl

N/A

not provided

not provided

In-house functionalisation of ZnO-1

Not applicable

Not applicable

Not applicable

12

not applicable

60 ± 5

Sonication in ultra-pure water, prepared immediately before use

7.8±0.88

N/A

N/A

not applicable

not provided

387±1

0.14

110±4

0.15

-17.9±0.2

-12.7±0.4

not provided

not provided

spherical

 

GSE39330_jurkat

Tuomela et al. 201371

https://doi.org/10.1371/journal.pone.0068415

Zinc oxide

ZnO-5

diethylene_glycol_ZnO

ZnO

none

diethylene glycol

N/A

not provided

not provided

In-house functionalisation of ZnO-1

Not applicable

Not applicable

Not applicable

12

not applicable

60 ± 5

Sonication in ultra-pure water, prepared immediately before use

5.4±0.5

N/A

N/A

not applicable

not provided

125±4

0.12

278±3

0.11

19.2±0.2

13.6±0.3

not provided

not provided

spherical

 

GSE39330_jurkat

Tuomela et al. 201371

https://doi.org/10.1371/journal.pone.0068415

Zinc oxide

ZnO-9

folic_acid_ZnO

ZnO

none

folic acid

N/A

not provided

not provided

In-house functionalisation of ZnO-1

Not applicable

Not applicable

Not applicable

12

not applicable

60 ± 5

Sonication in ultra-pure water, prepared immediately before use

N/A

40.4±2.6

404±8

not applicable

not provided

412±4

0.15

466±3

0.15

-31.7±0.3

-15.4±0.5

not provided

not provided

spherical

 

GSE45322

Osmond-McLeod et al. 201373

https://doi.org/10.1186/1743-8977-10-54

Zinc oxide uncoated

Zinc oxide uncoated

ZnO_ZCOTE

ZnO

none

uncoated

N/A

not provided

not provided

BASF

Germany

Z-COTE

EHDA3001

70-200

not applicable

12-14

Complete Hepatocyte Medium (HM, HM-5201)

N/A

44 ± 2

73 ± 4

not applicable

13 ± 2

400

0.3

260

0.3

27

8

not provided

Below detection limit

heterogeneous mix of rectangular-shaped particle

 

GSE45322

Osmond-McLeod et al. 201373

https://doi.org/10.1186/1743-8977-10-54

Zinc oxide uncoated

Zinc oxide uncoated

ZnO_Nanosun

ZnO

none

uncoated

N/A

not provided

not provided

Micronisers

Victoria, Australia

Nanosun P99/30

4051

30-50

not applicable

not available

Complete Hepatocyte Medium (HM, HM-5201)

25 ± 1

N/A

N/A

not applicable

30 ± 3

600

0.6

25

0.7

9

7

not provided

Below detection limit

rod-shaped

 

GSE45322

Osmond-McLeod et al. 201373

https://doi.org/10.1186/1743-8977-10-54

Zinc oxide

Zinc oxide coated

ZnO_HP1

ZnO

none

triethoxycaprylylsilane

N/A

not provided

not provided

BASF

Germany

Z-COTE HP1

CNHE0602

90-190

not applicable

12-14

Complete Hepatocyte Medium (HM, HM-5201)

N/A

28 ± 2

96 ± 6

not applicable

14.9 ± 0.5

240

0.3

300

0.6

-10

-10

not provided

Below detection limit

heterogeneous mix of rectangular-shaped particle

 

GSE45322

Osmond-McLeod et al. 201373

https://doi.org/10.1186/1743-8977-10-54

Zinc oxide

Zinc oxide coated

ZnO_MAX

ZnO

none

dimethoxydiphenylsilane/triethoxycaprylylsilane crosspolymer

N/A

not provided

not provided

BASF

Germany

Z-COTE MAX

FCHE1301

36-95

not applicable

not available

Complete Hepatocyte Medium (HM, HM-5201)

N/A

36 ± 2

95 ± 5

not applicable

12 ± 1

broad

1

90

0.2

-7

-6

not provided

Below detection limit

heterogeneous mix of rectangular-shaped particle

 

GSE51417

Teeguarden et al. 201474

https://doi.org/10.1186/s12989-014-0046-4

Superparamagnetic iron oxide particles (SPIO)

Fe3O4

SPIO

Iron Oxide

none

N(trimethoxysilylpropyl)ethylenediamine-triacetic

magnetite

not provided

not provided

In-house synthesized

Not applicable

Not applicable

Not applicable

12.8

not applicable

8.87 × 10−7 cm2 in 1 picogram

DI water

not given

not given

not given

not applicable

not provided

  

207

  

-41

good for coated ones

Not given

spherical

 

GSE51421

Aday et al. 201475

https://doi.org/10.1039/C4RA04041D

Poly(lactic acid-co-glycolic acid)

NP210-PFCE

PLGA

PLGA

None

protamine sulfate (cationic)

N/A

not provided

not provided

In-house synthesized

Not applicable

Not applicable

Not applicable

Not applicable

not applicable

 

M200 or QBSF-60

not given

not given

not given

not applicable

not provided

210

0.12 + 0.01

not provided

not provided

7.0 ± 1.7

not provided

not provided

Not given

spherical

 

GSE53700

Fede et al. 201476

https://doi.org/10.3390/ijerph110908867

Silica dioxide

AS30

SiO2_AS30

SiO2

ammounium counterions

None

N/A

not provided

not provided

Sigma Aldrich

St. Louis, MO, USA.

Ludox Silica - AS30

Not given

20

not applicable

~230

PBS

18 ± 3

N/A

N/A

not applicable

not provided

20 ± 4

 

150 with 3% serum (same as PBS in medium with no serum)

−25.9

not provided

not provided

Not given

spherical

  

GSE53700

Fede et al. 201476

https://doi.org/10.3390/ijerph110908867

Silica dioxide

SM30

SiO2_SM30

SiO2

sodium counterions

None

N/A

not provided

not provided

Sigma Aldrich

St. Louis, MO, USA.

Ludox Silica - SM30

Not given

10

not applicable

320-400

PBS

9 ± 3

N/A

N/A

not applicable

not provided

14 ± 4

 

150 with 3% serum (same as PBS in medium with no serum)

−26.3

not provided

not provided

Not given

spherical

  

GSE56324, GSE56325

Husain et al. 201577

https://doi.org/10.3109/17435390.2014.996192

Titanium dioxide

nano-TiO2

nanoTiO2

TiO2

none

Polyalcohol

Rutile

77.68

Si 5.61 wt%; Al 2.42 wt%; Zr 0.86 wt%; Na 0.45 wt %

Kemira

Pori, Finland

UV-Titan L181

Not given

20.6±0.3

not applicable

107.7

10% v/v acellular BAL collected from C57BL/6 mice

  

not applicable

not provided

4147±1260

0.882

not provided

not provided

not provided

not provided

1362±221 (0.253; 3.1 mm filtered) 1551±406 (0.722; 0.2 mm filtered)

Not given

spherical

  

GSE61366

Poulsen et al. 201578

https://doi.org/10.1016/j.taap.2015.01.011

Multi-walled CNT

CNTSmall (NRCWE-026)

MWCNT (NCRWE-026)

Carbon

none

none

N/A

87

Al2O3 (14.97%), Fe2O3 (0.29%), CoO (0.11%)

Nanocyl

Sambreville, Belgium

NC7000 CNT

Not given

11 ± 4.5

0.8 ± 0.1

245.8

2% serum collected from C57BL/6 mice

not given

not given

not given

not applicable

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

Not given

long tube

 

GSE61366

Poulsen et al. 201578

https://doi.org/10.1016/j.taap.2015.01.011

Multi-walled CNT

CNTLarge

MWCNT (NM-401)

Carbon

none

none

N/A

97

P2O5 (0.14%), CO3 (0.08%) and Fe2O3 -0.05%

IO-LE-TECNanomaterials

Supplied by JRC, Ispra

CP-0006-SG

NM-401 (Mitsui-7)

67 ± 26.2

4 ± 0.4

14.6

2% serum collected from C57BL/6 mice

not given

not given

not given

not applicable

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

Not given

long tube

 

GSE68036

Husain et al. 201579

https://doi.org/10.1016/j.taap.2015.11.003

Carbon black

CBNPs

Carbon black (Printex90)

Carbon

none

none

N/A

99%

< 1% polycyclic aromatic hydrocarbon

Evonik/Degussa

Frankfurt, Germany

Printex 90

Not given

14

not applicable

295–338

0.2 μm filtered, ɤ-irradiated Nanopure Diamond UV water

not given

not given

not given

not applicable

not provided

50-100

not provided

not provided

not provided

not provided

not provided

not provided

142

spherical

 

GSE84982_Caco2, GSE84982_MCF7

van der Zande et al. 201680

https://doi.org/10.1080/17435390.2016.1225132

Silver NPs

BioPure Ag-20

20nm_AgNPs

Ag

citrate

uncapped

N/A

99.99

not stated

Nanocomposix

San Diego, CA

EAW1091

                    

Not given

                                  
 

20.3±1.9

not applicable

27.6

DMEM + FBS

not given

not given

not given

not applicable

not provided

not provided

not provided

40±4

not provided

not provided

not provided

not provided

<5

spherical

                

GSE84982_Caco2, GSE84982_MCF7

van der Zande et al. 201680

https://doi.org/10.1080/17435390.2016.1225132

Silver NPs

BioPure Ag-30

30nm_AgNPs

Ag

citrate

uncapped

N/A

99.99

not stated

Nanocomposix

San Diego, CA

CTH1088

Not given

34.4±3.4

not applicable

14.2

DMEM + FBS

not given

not given

not given

not applicable

not provided

not provided

not provided

43±1

not provided

not provided

not provided

not provided

<2.5

spherical

 

GSE84982_Caco2, GSE84982_MCF7

van der Zande et al. 201680

https://doi.org/10.1080/17435390.2016.1225132

Silver NPs

BioPure Ag-60

60nm_AgNPs

Ag

citrate

uncapped

N/A

99.99

not stated

Nanocomposix

San Diego, CA

EAW1093

Not given

                   

61.2±5.3

                                  
 

not applicable

9.4

DMEM + FBS

not given

not given

not given

not applicable

not provided

not provided

not provided

88±2

not provided

not provided

not provided

not provided

<2.5

spherical

                 

GSE84982_Caco2, GSE84982_MCF7

van der Zande et al. 201680

https://doi.org/10.1080/17435390.2016.1225132

Silver NPs

BioPure Ag-100

110nm_AgNPs

Ag

citrate

uncapped

N/A

99.99

not stated

Nanocomposix

San Diego, CA

CTH1409

Not given

112.6±7.8

not applicable

5.7

DMEM + FBS

not given

not given

not given

not applicable

not provided

not provided

not provided

135±6

not provided

not provided

not provided

not provided

<2.5

spherical

 

GSE92899

Kinaret et al. 201781

https://doi.org/10.1021/acsnano.6b08650

long rigid MWCNT

rCNT

rCNT

Carbon

None

None

N/A

99.79 wt%

not stated

Mitsui & Co.

Tokyo, Japan

MWCNT-7

Not given

  

26

RPMI + 10% FBS

N/A

50

13000

not applicable

22

not given

not given

not given

not given

not given

not given

not given

Not given

tube

 

GSE92899

Kinaret et al. 201781

https://doi.org/10.1021/acsnano.6b08650

long tangled MWCNT

tCNT

tCNT

Carbon

None

None

N/A

>95

not stated

Cheaptubes Inc.

Grafton, VT, USA

Cheaptubes

Not given

8-15

10-50

233

RPMI + 10% FBS

N/A

11.5

30000

not stated

180

not given

not given

not given

not given

not given

not given

not given

not stated

tube

https://www.cheaptubes.com/product/multi-walled-carbon-nanotubes-8-15nm/

GSE92899

Kinaret et al. 201781

https://doi.org/10.1021/acsnano.6b08650

short tangled MWCNT

Baytube

MWCNT (Baytube)

Carbon

None

None

N/A

99

not stated

Bayer Material Science

Laufenburg, Germany

Baytubes C150 HP

Not given

5-20

1-10

not given

RPMI + 10% FBS

N/A

14.5

1000

not stated

204

not given

not given

not given

not given

not given

not given

not given

not stated

tube

Not produced anymore - no specification available

GSE92899

Kinaret et al. 201781

https://doi.org/10.1021/acsnano.6b08650

long rigid carbon fiber graphite

graphite

Graphite

Carbon

None

None

N/A

not stated

not stated

Sigma-Aldrich

Finland

636398

Not given

not given

not given

not given

RPMI + 10% FBS

N/A

140

10000

not applicable

32

not given

not given

not given

not given

not given

not given

not given

Not given

fibre

 

GSE92899

Kinaret et al. 201781

https://doi.org/10.1021/acsnano.6b08650

hollow carbon sphere

fullerene

Fullerene

Carbon

None

None

N/A

not stated

not stated

MTR Ltd.

Cleaveland, OH, USA

MTS60

Not given

1

not applicable

not stated

RPMI + 10% FBS

N/A

100

100

not applicable

20

not given

not given

not given

not given

not given

not given

not given

Not given

sphere

 

GSE92899

Kinaret et al. 201781

https://doi.org/10.1021/acsnano.6b08650

short rigid MWCNT

SES

MWCNT (SES)

Carbon

None

None

N/A

>95%

not stated

SES Research

Houston, Texas

900−1260

Not given

10-30

1-2

 

RPMI + 10% FBS

N/A

20

1500

not applicable

60

not given

not given

not given

not given

not given

not given

not given

Not given

tube

https://www.sesres.com/carbon-nanotubes/

GSE88786

Lastra et al. 201982

https://doi.org/10.33218/prnano2(4).190802.1

Fe3O4@TiO2

Fe3O4@TiO

Fe3O4_TiO2_NP

Fe3O4@TiO2

None

Dopamine

N/A

not stated

not stated

In-house produced

Not applicable

not provided

Not given

Not given

not applicable

Not given

Not given

Not given

Not given

Not given

not applicable

Not given

90

Not given

Not given

Not given

-27

Not given

stable for > 6 months

Not given

Not given

 

EMTAB6396_A549, EMTAB6396_Beas2B, EMTAB6396_MRC9, EMTAB6396_THP1

Scala & Kinaret et al. 201883

https://doi.org/10.1016/j.impact.2018.05.003

Carbon black

CBL

Carbon black

Carbon

None

None

N/A

not stated

not stated

Evonik

Germany

Printex 90

not stated

14

14

265

Cell culture medium + 1% FCS

Not given

Not given

Not given

not applicable

not given

not given

not given

not given

not given

not given

not given

not given

Not given

Particle

 

EMTAB6396_A549, EMTAB6396_Beas2B, EMTAB6396_MRC9, EMTAB6396_THP1

Scala & Kinaret et al. 201883

https://doi.org/10.1016/j.impact.2018.05.003

Fullerene C60

FUL

Fullerene

Carbon

None

None

N/A

not stated

not stated

MTR

not provided

not provided

not stated

100

100

20

Cell culture medium + 1% FCS

Not given

Not given

Not given

not applicable

not given

not given

not given

not given

not given

not given

not given

not given

not given

Sphere

 

EMTAB6396_A549, EMTAB6396_Beas2B, EMTAB6396_MRC9, EMTAB6396_THP1

Scala & Kinaret et al. 201883

https://doi.org/10.1016/j.impact.2018.05.003

Graphite nanofibers

GNF

Graphite nanofibers

Carbon

None

None

N/A

not stated

not stated

Sigma-Aldrich

not provided

not provided

not stated

10,000

140

32

Cell culture medium + 1% FCS

Not given

Not given

Not given

not stated

not given

not given

not given

not given

not given

not given

not given

not given

not given

Fiber

 

EMTAB6396_A549, EMTAB6396_Beas2B, EMTAB6396_MRC9, EMTAB6396_THP1

Scala & Kinaret et al. 201883

https://doi.org/10.1016/j.impact.2018.05.003

Singlewalled carbon nanotube

SIG_SW

SWCNT (Sigma)

Carbon

None

None

N/A

not stated

not stated

Sigma-Aldrich

not provided

not provided

not stated

50,000

1.1

567

Cell culture medium + 1% FCS

Not given

Not given

Not given

not stated

not given

not given

not given

not given

not given

not given

not given

not given

not given

Tube

 

EMTAB6396_A549, EMTAB6396_Beas2B, EMTAB6396_MRC9, EMTAB6396_THP1

Scala & Kinaret et al. 201883

https://doi.org/10.1016/j.impact.2018.05.003

Singlewalled carbon nanotube

SES_SW

SWCNT (SES)

Carbon

None

None

N/A

not stated

not stated

SES

not provided

not provided

not stated

1500

2

436

Cell culture medium + 1% FCS

Not given

Not given

Not given

not stated

not given

not given

not given

not given

not given

not given

not given

not given

not given

Tube

 

EMTAB6396_A549, EMTAB6396_Beas2B, EMTAB6396_MRC9, EMTAB6396_THP1

Scala & Kinaret et al. 201883

https://doi.org/10.1016/j.impact.2018.05.003

Multiwalled carbon nanotube

BAY_MW

MWCNT (Bayer)

Carbon

None

None

N/A

not stated

not stated

Bayer

not provided

not provided

not stated

1000

14.5

204

Cell culture medium + 1% FCS

Not given

Not given

Not given

not stated

not given

not given

not given

not given

not given

not given

not given

not given

not given

Tube

 

EMTAB6396_A549, EMTAB6396_Beas2B, EMTAB6396_MRC9, EMTAB6396_THP1

Scala & Kinaret et al. 201883

https://doi.org/10.1016/j.impact.2018.05.003

Multiwalled carbon nanotube

MIT_MW

MWCNT (Mitsui)

Carbon

None

None

N/A

not stated

not stated

Mitsui

not provided

not provided

not stated

13,000

50

22

Cell culture medium + 1% FCS

Not given

Not given

Not given

not stated

not given

not given

not given

not given

not given

not given

not given

not given

not given

Tube

 

EMTAB6396_A549, EMTAB6396_Beas2B, EMTAB6396_MRC9, EMTAB6396_THP1

Scala & Kinaret et al. 201883

https://doi.org/10.1016/j.impact.2018.05.003

Multiwalled carbon nanotube

SES_MW

MWCNT (SES)

Carbon

None

None

N/A

not stated

not stated

SES

not provided

not provided

not stated

1500

20

60

Cell culture medium + 1% FCS

Not given

Not given

Not given

not stated

not given

not given

not given

not given

not given

not given

not given

not given

not given

Tube

 

EMTAB6396_A549, EMTAB6396_Beas2B, EMTAB6396_MRC9, EMTAB6396_THP1

Scala & Kinaret et al. 201883

https://doi.org/10.1016/j.impact.2018.05.003

Multiwalled carbon nanotube

CHT_MW

MWCNT (Cheaptubes)

Carbon

None

None

N/A

not stated

not stated

cheaptubes

not provided

not provided

not stated

30,000

11.5

180

Cell culture medium + 1% FCS

Not given

Not given

Not given

not stated

not given

not given

not given

not given

not given

not given

not given

not given

not given

Tube

 

EMTAB6396_A549, EMTAB6396_Beas2B, EMTAB6396_MRC9, EMTAB6396_THP1

Scala & Kinaret et al. 201883

https://doi.org/10.1016/j.impact.2018.05.003

Multiwalled carbon nanotube

SIG_MW

MWCNT (Sigma)

Carbon

None

None

N/A

not stated

not stated

Sigma-Aldrich

not provided

not provided

not stated

100,000

15

119

Cell culture medium + 1% FCS

Not given

Not given

Not given

not stated

not given

not given

not given

not given

not given

not given

not given

not given

not given

Tube

 

GSE100500

Mohan et al. 201884

https://doi.org/10.1152/ajplung.00289.2017

Multi-walled CNTs

MWCNT

MWCNT

Carbon

None

None

N/A

99

<1% Fe

SES research

Houston, TX

900–1501

GS1801

20-40

20-40

not given

  

20–40

 

not stated

85.75

-46.3

 

850 ± 20 (160  ±  20 after centrifugation)

  

stable

  

https://www.sesres.com/carbon-nanotubes/

 

GSE113088

Vis et al. 201886

https://doi.org/10.1021/acsnano.8b03363

Silica

USSN

nanoSiO2

Silica dioxide

None

None

N/A

not stated

not stated

In-house synthesized

Not applicable

Not applicable

Not applicable

3.6 ± 0.5

not applicable

not given

                

GSE14452

Kawata et al. 200987

https://doi.org/10.1080/15287394.2016.1159635

Silver

Ag

AgNPs

Ag

polyethylenimine

None

N/A

not stated

not stated

Kyoto Nano Chemical Co., Ltd.

Kyoto, Japan

not provided

not provided

7-10

not applicable

not given

MEM

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

spherical

 

GSE14452

Kawata et al. 200987

https://doi.org/10.1021/es900754q

PS

PS

PS

PS

None

None

N/A

not stated

not stated

Micromod

Germany

micromerR

not provided

15

not applicable

not given

MEM

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

spherical

 

GSE14452

Kawata et al. 200987

https://doi.org/10.1021/es900754q

Ag2CO3

ionic control

Ag2CO3

None

None

None

N/A

not stated

not stated

Wako Pure Chemical Industries

Osaka, Japan

not provided

not provided

not provided

not applicable

not given

MEM

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

N/A

 

GSE14452

Kawata et al. 200987

https://doi.org/10.1021/es900754q

Ag NPs + cysteine, a strong Ag+ ligand

N/A

AgNPs_cysteine

Ag

polyethylenimine

None

N/A

not stated

not stated

Kyoto Nano Chemical Co., Ltd.

Kyoto, Japan

not provided

not provided

7-10

not applicable

not given

MEM

               

GSE17676

Peng et al. 201088

https://doi.org/10.1021/nl903043z

TiO2 nanotube array

TiO2-30

TiO2 nanotubes (30nm)

TiO2

None

None

anatase

>99%

not stated

In-house synthesized by anodic oxidation in an

                      

electrolytic solution

Not applicable

Not applicable

not provided

30

1

not given

Surface array

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not provided

vertical array

             

GSE17676

Peng et al. 201088

https://doi.org/10.1021/nl903043z

TiO2 nanotube array

TiO2-100

TiO2 nanotubes (100nm)

TiO2

None

None

anatase

>99%

not stated

In-house synthesized by anodic oxidation in an

                      

electrolytic solution

Not applicable

Not applicable

not provided

100

1

not given

Surface array

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not provided

vertical array

             

GSE19487_liver, GSE19487_lung

Halappanavar et al. 201189

https://doi.org/10.1002/em.20639

nanoTiO2

TiO2

nanoTiO2

TiO2

None

polyalcohol

rutile

not stated

zirconium, silicon, aluminum

Kemira

Pori, Finland

UV-titan L181

not provided

20

needle shaped

70

     

107.7

100 - 4,000

         

GSE20692

Eom et al. 201490

https://doi.org/10.1016/j.toxlet.2014.05.019

Ag NPs

AgNPs

AgNPs

Ag

not stated

none

N/A

>99%

not stated

Sigma–Aldrich Chemical

St. Louis, MO, USA

not provided

<100

not applicable

 

dispersed in THF, then filtered through 100nm cellular acetate membrane

5−10

not applicable

not applicable

not given

not given

not given

28−35

not given

 

not given but < -30 mV

slightly agglomerated particles

not provided

spherical

   

GSE27212

Fabbro et al. 201391

https://doi.org/10.1371/journal.pone.0073621

Multiwalled carbon nanotube

CNT

MWCNT

Carbon

pyrrolidine groups

None

N/A

>90%

<10% metal

Nanostructured & Amorphous Materials, Inc.

Katy, TX 77494, USA

not provided

not provided

20-30

not applicable

55

deposited on glass coverslip

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

deposited on surface

not provided

Nanotube Conductive Scaffold

https://www.nanoamor.com/coa/coa_MWNT_1221YJ.pdf

GSE29110

Langley et al. 201192

https://doi.org/10.1080/15287394.2011.595669

SiO2

SiO2

Silica

None

None

N/A

N/A

99.20%

Al2O3 (0.03%), Fe2O3 (0.04%), TiO2 (0.02%)

U.S. Silica

Mill Creek, OK, USA

Min-U-Sil 5

not provided

1750 ± 50

not applicable

not given

aerosolized

not given

not given

not given

not given

not given

not given

not given

not given

not given

not given

not given

aersoloized

not provided

spherical

http://www.wrchem.com/wp-content/uploads/2015/11/MIN-U-Sil-5-Ground-Silica-TDS.pdf

GSE30178, GSE30180, GSE30213, GSE30214

Sellamuthu et al. 201165

https://doi.org/10.3109/08958378.2011.625995

Aerosolized silica

SiO2

Silica

None

None

N/A

N/A

99.20%

Al2O3 (0.03%), Fe2O3 (0.04%), TiO2 (0.02%)

US Silica

Berkeley Springs, WV, USA

Min-U-Sil 5

not provided

1750 ± 50

not applicable

not given

Sieved through a 10 μm mesh filter, serum-free F-12K

 

not provided

not applicable

not provided

not provided

not provided

not provided

not provided

 

not provided

Endotoxin-free

spherical

   

GSE44294

Kodali et al. 201393

https://doi.org/10.1021/nn402145t

Superparamagnetic iron oxide (SPIO)

Fe3O4

SPIO

Fe3O4

None

None

N/A

not given

not given

Synthesis in-house

Not applicable

Not applicable

Not applicable

13

not applicable

 

RPMI

13

not applicable

not provided

not applicable

not provided

453

not provided

274

not provided

-33

-21.9

not provided

<0.01 EU/ml

spherical

 

GSE44294

Kodali et al. 201393

https://doi.org/10.1021/nn402145t

Fluorescent-labeled amorphous silica nanospheres

SiO2

SiO2

SiO2

None

None

N/A

not given

not given

Corpuscular Inc.

Cold Spring, USA

not provided

not provided

50

not applicable

 

RPMI

50

not applicable

not provided

not applicable

not provided

87

not provided

87

not provided

-24

-23.5

not provided

<0.01 EU/ml

spherical

 

GSE45598, GSE45868

Hussien et al. 201394

https://doi.org/10.1002/phy2.27

polymeric Eudragit RS NPs

Eudragit

Eudragit_RS

ethylacrylate and methylmethacrylate

quaternary ammonium groups

N/A

not given

not given

Evonik Industries

Essen, Germany

Eudragit RS 100 copolyme

Prepared in-house into NPs ((Eidi et al. 2010)

not applicable

not provided

not provided

not provided

not provided

not provided

not applicable

not provided

not provided

not provided

65.0 ± 26.3

not provided

+51.04

 

not provided

not provided

spherical

   

GSE4567

Karoly et al. 200795

https://doi.org/10.1289/ehp.9556

Ambient ultrafine particles

UFP

UFP

Mixed

None

none

N/A

not given

Al, Cu, Fe, Pb, Si, Zn most abundant (Becker et al. 2005)

UFPs collected July 2002, Chapel Hill, North Carolina, outside US EPA health facility

not provided

not provided

not provided

not applicable

not provided

not provided

not provided

not provided

not provided

not applicable

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

spherical

  

GSE48087

Chorley et al. 201496

https://doi.org/10.1016/j.neuro.2014.08.010

Ag NPs

Ag-10 cit

Ag10_Citrate

Ag

Citrate

none

N/A

>99.5

not stated

nanoComposix Inc.

San Diego, CA, USA

not provided

not provided

10

not applicable

53.7

0.2 mM citrate buffer

9.9 ± 1.9

Not appliable

Not appliable

not applicable

not given

7.5

low

not given

not given

not given

−10.28

monodispersed, monomodal

< 5

spherical

https://tools.nanocomposix.com:48/cdn/coa/Silver/Spheres/BioPure/AG10-SS-BP-CIT-HKE0021.pdf?107%20953

GSE48087

Chorley et al. 201496

https://doi.org/10.1016/j.neuro.2014.08.010

Ag NPs

Ag-10 PVP

Ag10_PVP

Ag

Citrate

PVP

N/A

>99.5

not stated

nanoComposix Inc.

San Diego, CA, USA

not provided

not provided

10

not applicable

53.5

0.2 mM citrate buffer

10.1 ± 1.8

Not appliable

Not appliable

not applicable

not given

60

low

not given

not given

not given

−7.25

monodispersed, monomodal

< 5

spherical

https://nanocomposix.com/collections/material-silver/products/biopure-silver-nanospheres-bare-citrate?variant=15906775597145#specs

GSE48087

Chorley et al. 201496

https://doi.org/10.1016/j.neuro.2014.08.010

Ag NPs

Ag-75 cit

Ag75_Citrate

Ag

None

PVP

N/A

>99.5

not stated

nanoComposix Inc.

San Diego, CA, USA

not provided

not provided

75

not applicable

 

HBSS

 

Not appliable

Not appliable

not applicable

not given

7.148 

low

not given

not given

not given

−10.73

monodispersed, monomodal

< 2.5

spherical

https://tools.nanocomposix.com:48/cdn/coa/Silver/Spheres/BioPure/AG10-SS-BP-PVP-HKE0023.pdf?107%20953

GSE48087

Chorley et al. 201496

https://doi.org/10.1016/j.neuro.2014.08.010

Ag NPs

Ag-75 PVP

Ag75_PVP

Ag

none

PVP

N/A

>99.5

not stated

nanoComposix Inc.

San Diego, CA, USA

not provided

not provided

75

not applicable

7.5

HBSS

74.1 ± 8.2

Not appliable

Not appliable

not applicable

not given

70

low

not given

not given

not given

−6.27

monodispersed, monomodal

< 2.5

spherical

https://tools.nanocomposix.com:48/cdn/coa/Silver/Spheres/OECD/AG75-SS-BP-PVP-OECD-KJW1856.pdf?107%20953

GSE50176

Rydman et al. 201497

https://doi.org/10.1186/s12989-014-0048-2

long tangled MWCNT

tCNT

tCNT

Carbon

None

None

N/A

99.76 wt%

<1 wt% Ni and Fe

Cheap Tubes Inc.

Grafton, VT, USA

MWNTs 8-15 nm OD

not provided

8-15 (OD)

10-50

233

aerosolized

     

not provided

not provided

not provided

not provided

not provided

not provided

not provided

<0.022

long tubes

 

GSE50176

Rydman et al. 201497

https://doi.org/10.1186/s12989-014-0048-2

long rigid MWCNT

rCNT

rCNT

Carbon

None

None

N/A

99.79 wt%

0.1 wt %

Mitsui & Co., Ltd.

 

XNRI MWNT-7

not provided

>50 (OD)

~13

26

aerosolized

     

not provided

not provided

not provided

not provided

not provided

not provided

not provided

<0.022

long tubes

 

GSE51636

Chernova et al. 201798

https://doi.org/10.1016/j.cub.2017.09.007

Long Carbon Nanotubes

LNT

Long_carbon_nanotubes

Carbon

None

None

N/A

not stated

Fe (37.3), Cu (1.2), Ni (6.2) and Co (3.4)

University of Manchester, Produced and characterized by Dr. Ian Kinloch

Manchester, UK

not provided

not provided

20–100

 

20–1nh0en

DI water + 0.5%BSA

165.02 ± 4.68

not given

Not appliable

not applicable

 

not provided

not provided

not provided

not provided

not provided

not provided

not provided

<10 

long tubes

 

GSE51636

Chernova et al. 201798

https://doi.org/10.1016/j.cub.2017.09.007

South African amosite - long

LFA

Long_asbestos_fibres

Asbestos

None

None

amosite

not stated

Cd <0.1; Cr1.4; Co 3.4; Cu 5.2; Fe 853; Mn 104.8; Ni 5.1; Ti 2.0; V <0.1; Zn 27.3

Manville Corporation

USA

not provided

not provided

not stated

not stated

not stated

DI water + 0.5%BSA

1000

not given

Not appliable

not applicable

 

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

long tubes

 

GSE51636

Chernova et al. 201798

https://doi.org/10.1016/j.cub.2017.09.007

South African amosite - short

SFA

Short_asbestos_fibres

Asbestos

None

None

amosite

not stated

Cd <0.1; Co 2.1; Cr <0.1; Cu 3.1; Fe 547; Mn 36.3; Ni 18.4; Ti 31.5; Vn 3.1; Zn 10.5

Manville Corporation

USA

not provided

not provided

not stated

not stated

not stated

DI water + 0.5%BSA

700

not given

Not appliable

not applicable

 

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

long tubes

 

GSE51636

Chernova et al. 201798

https://doi.org/10.1016/j.cub.2017.09.007

Short Carbon Nanotubes

SNT

Short_carbon_nanotubes

Carbon

None

None

N/A

not stated

Cd <0.1; Cr <0.1; Co <0.1; Cu <0.1; Fe 24.2; Mn 50.3; Ni 21.6; Ti 0.4; V <0.1; Zn 5.3

Nanostructured & Amorphous Materials

TX, USA

#1246YJS

not provided

not stated

not stated

not stated

DI water + 0.5%BSA

125

not given

Not appliable

not applicable

 

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

long tubes

 

GSE51661

Aday et al. 201475

https://doi.org/10.1039/C4RA04041D

Poly(lactic acid-co-glycolic acid)

NP210-PFCE

PLGA

PLGA

protamine sulfate (cationic)

None

N/A

not stated

not stated

In-house synthesized

Not applicable

Not applicable

Not applicable

not givem

not applicable

not given

M200 or QBSF-60

not provided

not provided

not provided

not provided

not provided

210

0.12 + 0.01

not provided

not provided

7.0 ± 1.7

not provided

not provided

not given

spherical

 

GSE7010

Huang et al. 201199

https://doi.org/10.1080/15287394.2010.516238

Particulate matter

PM coarse

Chapel_hill_coarse

Nitrate & metals

None

None

crustal material (Al, Fe, and Si)

not stated

Collected Oct 2010, Chapel Hill, NC, outside the U.S. EPA

not provided

2500-10000

not applicable

2500ru0etg

sterile distilled water

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

roughly spherical

    

GSE7010

Huang et al. 201199

https://doi.org/10.1080/15287394.2010.516238

Particulate matter

PM fine

Chapel_hill_fine

Nitrate & metals

None

None

N/A

not stated

As, Pb, V, Zn, Br, EC

Collected Oct 2010, Chapel Hill, NC, outside the U.S. EPA

not provided

100-2500

not applicable

100-ru0etg

sterile distilled water

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

roughly spherical

   

GSE7010

Huang et al. 201199

https://doi.org/10.1080/15287394.2010.516238

Particulate matter

PM ultrafine

Chapel_hill_UFP

Nitrate & metals

None

None

N/A

not stated

As, Pb, V, Zn, Br, EC

Collected Oct 2010, Chapel Hill, NC, outside the U.S. EPA

not provided

<100

not applicable

not given

sterile distilled water

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

not provided

roughly spherical

   

GSE79766

Gao et al. 2017100

https://doi.org/10.1186/s12951-017-0265-6

Silver NPs

BioPure Ag-20

AgNPs

Ag

citrate

None

N/A

99.99

not stated

Nanocomposix

San Diego, CA

not provided

not provided

20

not applicable

not given

ESGRO Complete Basal Medium

20.4 ± 3.2

not applicable

not applicable

not applicable

not given

20.4 ± 3.2

0.29

78.6

0.048

−39.8 (2mM citrate)

not given

monodispersed, monomodal

<5

spherical

https://tools.nanocomposix.com:48/cdn/coa/Silver/Spheres/BioPure/AG20-SS-BP-CIT-SCM0069.pdf?107%20953

GSE82062

Guo et al. 2017101

https://doi.org/10.1080/17435390.2017.1403658

Amorphous SiO2

Silica

nanoSiO2

SiO2

None

None

N/A

>99.9%

not stated

In-house synthesis using Stober method

not applicable

not applicable

Not applicable

60

not applicable

not given

DMEM

57.66 ± 7.30

not applicable

not applicable

not applicable

not given

not given

not given

106

not given

not given

−32

monodispersed, monomodal

not given

spherical

not applicable

GSE85711

Kinaret et al. 2017102

https://doi.org/10.1021/acsnano.6b05652

long tangled MWCNT

tCNT

tCNT

Carbon

None

None

N/A

99.76 wt%

<1 wt% Ni and Fe

Cheap Tubes Inc.

Grafton, VT, USA

MWNTs 8-15 nm OD

not provided

8-15 (OD)

10-50

233

aerosolized

            

<0.022

long tubes

 

GSE85711

Kinaret et al. 2017102

https://doi.org/10.1021/acsnano.6b05652

long rigid MWCNT

rCNT

rCNT

Carbon

None

None

N/A

99.79 wt%

0.1 wt %

Mitsui & Co., Ltd.

 

XNRI MWNT-7

not provided

>50 (OD)

~13

26

aerosolized

            

<0.022

long tubes

 

GSE92563

Proquin et al. 2018103

https://doi.org/10.1016/j.dib.2017.11.067

Titanium dioxide

E171

TiO2 (E171)

TiO2

None

None

anatase

99%

Al2O3 and/or SiO2

Sensient Technologies Company

Mexico

not given

not given

120

not applicable

not applicable

water

not given

not applicable

not applicable

not applicable

not given

not given

not given

316.8 ± 282.4

not given

not given

−12.78 ± 0.52

E171 comprises 2 fractions : 39% NPs and 61% MPs

rounded / spherical

Couldn’t find the specific one used

 

GSE92900

Kinaret et al. 201781

https://doi.org/10.1021/acsnano.6b08650

long rigid MWCNT

rCNT

rCNT

Carbon

None

None

N/A

99.79 wt%

not stated

Mitsui & Co.

Tokyo, Japan

MWCNT-7

Not given

  

26

PBS with 0.6 mg of BSA/mL

N/A

50

13000

not applicable

22

not given

not given

not given

not given

not given

not given

not given

Not given

tube

 

GSE92900

Kinaret et al. 201781

https://doi.org/10.1021/acsnano.6b08650

long tangled MWCNT

tCNT

tCNT

Carbon

None

None

N/A

>95

not stated

Cheaptubes Inc.

Grafton, VT, USA

Cheaptubes

Not given

8-15

10-50

233

PBS with 0.6 mg of BSA/mL

N/A

11.5

30000

not stated

180

not given

not given

not given

not given

not given

not given

not given

not stated

tube

https://www.cheaptubes.com/product/multi-walled-carbon-nanotubes-8-15nm/

GSE92900

Kinaret et al. 201781

https://doi.org/10.1021/acsnano.6b08650

short tangled MWCNT

Baytube

MWCNT (Baytube)

Carbon

None

None

N/A

99

not stated

Bayer Material Science

Laufenburg, Germany

Baytubes C150 HP

Not given

5-20

1-10

not given

PBS with 0.6 mg of BSA/mL

N/A

14.5

1000

not stated

204

not given

not given

not given

not given

not given

not given

not given

not stated

tube

Not produced anymore - no specification available

GSE92900

Kinaret et al. 201781

https://doi.org/10.1021/acsnano.6b08650

long rigid carbon fiber graphite

graphite

Graphite

Carbon

None

None

N/A

not stated

not stated

Sigma-Aldrich

Finland

636398

Not given

not given

not given

not given

PBS with 0.6 mg of BSA/mL

N/A

140

10000

not applicable

32

not given

not given

not given

not given

not given

not given

not given

Not given

fibre

 

GSE92900

Kinaret et al. 201781

https://doi.org/10.1021/acsnano.6b08650

hollow carbon sphere

fullerene

Fullerene

Carbon

None

None

N/A

not stated

not stated

MTR Ltd.

Cleaveland, OH, USA

MTS60

Not given

1

not applicable

not stated

PBS with 0.6 mg of BSA/mL

N/A

100

100

not applicable

20

not given

not given

not given

not given

not given

not given

not given

Not given

sphere

 

GSE92900

Kinaret et al. 201781

https://doi.org/10.1021/acsnano.6b08650

short rigid MWCNT

SES

MWCNT (SES)

Carbon

None

None

N/A

>95%

not stated

SES Research

Houston, Texas

900−1260

Not given

10-30

1-2

 

PBS with 0.6 mg of BSA/mL

N/A

20

1500

not applicable

60

not given

not given

not given

not given

not given

not given

not given

Not given

tube

https://www.sesres.com/carbon-nanotubes/

GSE92987

Kalmodia et al. 2017104

https://doi.org/10.1016/j.omtn.2017.10.012

Functionalised gold NPs

GNPs

AuNPs

Gold

citrate

none

N/A

not given

not given

In-house synthesis using extracts of Vitis vinefera L.

not applicable

not applicable

not applicable

not provided

not applicable

not provided

water

Not given

Not applicable

Not applicable

Not applicable

not given

not given

not given

24.47 ± 0.028

0.388

not given

-18.2

monodispersed, monomodal

not given

spherical

not applicable

GSE92987

Kalmodia et al. 2017104

https://doi.org/10.1016/j.omtn.2017.10.012

Functionalised gold NPs

GNPs

AuNPs-HDM2

Gold

none

HDM2

N/A

not given

not given

In-house synthesis using extracts of Vitis vinefera L.

not applicable

not applicable

not applicable

not provided

not applicable

not provided

water

Not given

Not applicable

Not applicable

Not applicable

not given

not given

not given

66.72 ± 2.83

0.303

not given

-11.4

monodispersed, monomodal

not given

spherical

not applicable

GSE96720

Li et al. 2018105

https://doi.org/10.1093/toxsci/kfy090

Functionalised Graphene oxide

OH-GQDs

Graphene quantum dots (GQD)

Carbon

hydroxyl

none

N/A

not given

not given

XFNANO Materials Tech Co.

Nanjing, China

XF091

not provided

4-6

not applicable

not given

RPMI 1640 or DMEM

4-6

Not applicable

not applicable

Not applicable

not given

14.1 ± 2.3

not given

not given

not given

not given

not given

monodispersed, monomodal

not given

spheres

https://www.xfnano.com/HaodeUpload/productfile/201904/20190417/XF091-%E7%BE%9F%E5%9F%BA%E5%8C%96%E7%9F%B3%E5%A2%A8%E7%83%AF%E9%87%8F%E5%AD%90%E7%82%B9%20-%20%E7%AC%AC%E4%BA%8C%E6%AC%A1%E4%BF%AE%E8%AE%A220180925.pdf

GSE99929_Jurkat, GSE99929_THP1

Orecchioni et al. 2017106

https://doi.org/10.1038/s41467-017-01015-3

Graphene oxide

GO

GO

Carbon

none

none

N/A

not stated

not stated

In-house produced from graphite flakes (Barnwell, UK) using modified Hummers’ method (Ali-Boucetta et al. 2013)

not applicable

not applicable

not applicable

<300 

<300 

not given

RPMI-1640 with FBS 10%

1

245.7 ± 57.1

N/A

2-3 layers

not given

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not described

not given

sheets

not applicable

GSE99929_Jurkat, GSE99929_THP1

Orecchioni et al. 2017106

https://doi.org/10.1038/s41467-017-01015-3

Amine-modified Graphene oxide

GONH2

GONH2

Carbon

triethyleneglycol (TEG) diamine

none

N/A

not stated

not stated

In-house produced from graphite flakes (Barnwell, UK) using modified Hummers’ method (Ali-Boucetta et al. 2013)

not applicable

not applicable

not applicable

<300 

<300 

not given

RPMI-1640 with FBS 10%

1

184.4 ±  115.4

N/A

2-3 layers

not given

not applicable

not applicable

not applicable

not applicable

not applicable

not applicable

not described

not given

sheets

not applicable

GSE101992

Yazdimamaghani et al. 2020109

https://doi.org/10.1016/j.nano.2017.11.021

Silica dioxide

Stöber 50 a

Silica NPs (Stober50)

SiO2

none

none

N/A

not stated

not stated

In-house prodced using a modified Stober method

N/A

N/A

N/A

46

N/A

N/A

RPMI + 10% FBS

46 ± 4.9

N/A

N/A

N/A

186.03

108.1 ± 6.3

not given

190.5 ± 4.8

not given

−40.3 ± 1.9

−9.57 ± 0.4

monodispersed, monomodal

not given

spherical

not applicable

GSE101992

Yazdimamaghani et al. 2020109

https://doi.org/10.1016/j.nano.2017.11.021

Silica dioxide

Stöber 500 a

Silica NPs (Stober500)

SiO2

none

none

N/A

not stated

not stated

In-house prodced using a modified Stober method

N/A

N/A

N/A

436

N/A

N/A

RPMI + 10% FBS

432 ± 18.7

N/A

N/A

N/A

6.83

520.3 ± 4.8

not given

539.7 ± 6.2

not given

−53.1 ± 1.5

−9.48 ± 0.5

monodispersed, monomodal

not given

spherical

not applicable

GSE101992

Yazdimamaghani et al. 2020109

https://doi.org/10.1016/j.nano.2017.11.021

Silica dioxide

MSN500 a

Silica NPs (MSN500)

SiO2

none

none

mesoporous

not stated

not stated

In-house prodced using a modified Stober method

N/A

N/A

N/A

462

N/A

N/A

RPMI + 10% FBS

466 ± 86

N/A

N/A

N/A

950.09

799.8 ± 22.9

not given

915 ± 72

not given

−44 ± 0.8

−8.03 ± 0.5

monodispersed, monomodal

not given

spherical

not applicable

GSE101992

Yazdimamaghani et al. 2020109

https://doi.org/10.1016/j.nano.2017.11.021

Silica dioxide

MSN500-PEG

Silica NPs (MSN_PEG500)

SiO2

none

PEG (10kD)

mesoporous

not stated

not stated

In-house prodced using a modified Stober method

N/A

N/A

N/A

462

N/A

N/A

RPMI + 10% FBS

466 ± 86

N/A

N/A

N/A

526.29

706.5 ± 22.2

not given

757 ± 62

not given

−34.3 ± 0.7

−8.56 ± 0.8

monodispersed, monomodal

not given

spherical

not applicable

GSE125742_HBMSC, GSE125742_HUVEC, GSE125742_mouse_bone, GSE125742_mouse_heart, GSE125742_mouse_kidney, GSE125742_mouse_liver, GSE125742_mouse_muscle, GSE125742_mouse_MuscleStemCell, GSE125742_mouse_PBMC, GSE125742_mouse_spleen

Wu et al. 2019110

https://doi.org/10.1016/j.biomaterials.2019.03.019

Hydroxyapatite

HANP

Hydroxyapatite

Ca10(PO4)6(OH)2

none

none

N/A

not stated

not stated

Ji’nan Daigang Biomaterial Co. Ltd.

Shandong, China

not given

not given

20

80

not given

saline (0.9% sodium chloride)

N/A

20

80

N/A

not provided

not provided

not provided

100

not provided

not provided

not provided

partially agglometated in medium

not given

rod-shaped

not available

GSE143717

House et al. 2020108

https://doi.org/10.1002/smll.202000299

AgNPs

Ag-cit

AgNPs_Citrate

Ag

citrate

None

N/A

99.90%

not stated

nanoComposix

San Diego, CA, USA

WJT0044

not given

40

N/A

14.2

DMEM

41 ± 5

N/A

N/A

N/A

not provided

42

not provided

96.75±5.48

not provided

-49

not provided

monodispersed, monomodal

< 2.5

spherical

https://tools.nanocomposix.com:48/cdn/coa/Silver/Spheres/BioPure/AG40-SS-BP-CIT-JEA0271.pdf?107%20953

GSE143717

House et al. 2020108

https://doi.org/10.1002/smll.202000299

AgNPs

Ag-PEG

AgNPs_polyethylene_glycol

Ag

none

PEG

N/A

99.90%

not stated

nanoComposix

San Diego, CA, USA

AGGB40

CWW0059

40

N/A

13.8

DMEM

39 ± 4

N/A

N/A

N/A

not provided

60

not provided

71.00±1.97

not provided

-29

not provided

monodispersed, monomodal

< 2.5

spherical

https://tools.nanocomposix.com:48/cdn/coa/Silver/Spheres/BioPure/AG40-SS-BP-PEG-JCP1525.pdf?107%20953

GSE143717

House et al. 2020108

https://doi.org/10.1002/smll.202000299

AgNPs

Ag-bPEI

AgNPs_branched_polyethylenimine

Ag

none

branched PEI

N/A

99.90%

not stated

nanoComposix

San Diego, CA, USA

AGGB40

PSK0027

40

N/A

14.4

DMEM

39 ± 3

N/A

N/A

N/A

not provided

65

not provided

149.14±15.95

not provided

63.5

not provided

monodispersed, monomodal

< 2.5

spherical

https://tools.nanocomposix.com:48/cdn/coa/Silver/Spheres/BioPure/AG40-SS-BP-BPEI-SCM0040.pdf?107%20953

GSE153419

Yang & Landry 2020111

https://doi.org/10.1101/2020.06.30.181420

Short SWCNTs

(GT)6 SWCNT

(GT)6 SWCNT

Carbon

none

(GT)6 DNA

N/A

not given

not given

NanoIntegris

Quebec, Canada

HiPco™SWCNTs

not given

~0.8 – 1.2

~100 – 1000

~400 – 1000

DMEM/F12 + 10% FBS

not given

not given

not given

1

not given

not given

not given

not given

not given

not given

not given

not given

Below detection limit

short tubes

http://nanointegris.com/our-products/small-diameter-swnts-hipco/

GSE153419

Yang & Landry 2020111

https://doi.org/10.1101/2020.06.30.181420

SWCNTs

SWCNT-COOH

Carboxylated SWCNT

Carbon

COOH

None

N/A

>90%

5-8% metals

Sigma Aldrich

USA

COOH-SWCNTs

not given

4-5

0.5-1.5

 

DMEM/F12 + 10% FBS

not given

not given

not given

1

not given

not given

not given

not given

not given

not given

not given

not given

Below detection limit

short tubes

https://api.sigmaaldrich.com/deepweb/assets/sigmaaldrich/quality/spec/401/763/652490-BULK_______ALDRICH__.pdf

GSE155027

Kang et al. 2020107

https://doi.org/10.1038/s41598-020-70415-1

Ag2S NPs

Ag2S

Ag2S

Ag

none

none

monoclinic

not stated

not stated

In-house synthesized

N/A

N/A

N/A

N/A

N/A

N/A

DMEM + 10% FBS

<10

N/A

N/A

N/A

N/A

25.67

0.56

not given

not given

31.73

not given

not given

not given

spherical

not applicable

GSE155027

Kang et al. 2020107

https://doi.org/10.1038/s41598-020-70415-1

Li-doped Ag2S NPs

Li-doped Ag2S

Li-doped Ag2S

Ag

none

none

monoclinic

not stated

not stated

In-house synthesized

N/A

N/A

N/A

N/A

N/A

N/A

DMEM + 10% FBS

<10

N/A

N/A

N/A

N/A

53.08

0.379

not given

not given

26.38

not given

not given

not given

spherical

not applicable

GSE86339_C57Bl6, GSE86339_DBA2

Frank et al. 2017112

https://doi.org/10.1016/j.taap.2017.04.019

Multi-walled CNTs

MWCNT

MWCNT

Carbon

none

none

N/A

99

negligible metal content

Baytubes

Leverkusen, German

not given

not given

N/A

10.7

>1

PBS with 1% Pluronic F127

N/A

10.7±3.1

>1

N/A

193.6

not given

not given

not given

not given

not given

not given

loose agglomerates of fibers

Below detection limit

tangled morphology

not available