Fig. 6
From: Simultaneous visualization of DNA loci in single cells by combinatorial multi-color iFISH
Correlation between genomic and physical distances. (a) Distributions of all possible pairwise distances, separately for the subset of 16 miFISH probes spaced 3 or 20 Mb apart on the linear genome. n, number of probe pairs analyzed. P, p-value (Wilcoxon test, two-tailed). In the violin plots, the horizontal lines indicate the first, second (median) and third quartile (from bottom to top), and the whiskers extend from the minimum to the maximum value. (b) Correlation between the median pairwise 3D distances and the corresponding genomic distances for all possible pairs of 16 miFISH probes (Dataset 123). The pairwise distances are displayed in logarithmic scale on both axes. Each dot represents one of 120 possible probe pairs using the 16 miFISH probes. n, number of probe pairs analyzed. From 20 Mb upwards, the pairwise distances increase exponentially. Each dot is colored based on the normalized distance from the lamina (see Methods for how the normalization was done).
