Table 1 Baseline characteristics of patients in the TACERA study.

From: RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients

Characteristics

Baseline (n = 267)

Age, years

53.1 (15.2)

Female

192 (71.9%)

White Ethnicity

194 (72.7%)

BMI

  Female

27.53 (6.47)

  Male

27.43 (4.97)

  Overall

27.50 (6.08)

BMI Status

  Underweight: <18.5

9 (3.4%)

  Healthy weight: (18.5,25)

85 (31.8%)

  Overweight: (25,30)

95 (35.6%)

  Obese: ≥30

78 (29.2%)

Smoking

  Never smoked

95 (35.6%)

  Previous smoker

104 (39.0%)

  Current smoker

68 (25.4%)

Alcohol consumption

  None

86 (32.3%)

  1–5 units per week

115 (43.2%)

  6–10 units per week

25 (9.4%)

  11–15 units per week

11 (4.1%)

  16–20 units per week

15 (5.7%)

  More than 20 units per week

14 (5.3%)

Alcohol frequency

  Not Drinking

86 (32.2%)

  1–2 days a year

28 (10.5%)

  1–2 days a month

48 (18.0%)

  1–2 days a week

58 (21.7%)

  3–4 days a week

28 (10.5%)

  5 days or more a week

19 (7.1%)

Rheumatoid Factor (RF) positive

247 (92.5%)

Anti-citrullinated protein antibody (ACPA) positive

230 (86.1%)

Disease Duration (years)

0.43 (0.23)

X-ray Larsen’s Score (hands and feet)

6.70 (8.76)

Charlson’s Comorbidity Index (original)

0.44 (0.84)

Charlson’s Comorbidity Index (2008)

0.81 (1.10)

SDAI

28.80 (14.29)

DAS28-CRP

4.85 (1.22)

Prescribed Medication

  Methotrexate (MTX)

202 (75.7%)

  Hydroxychloroquine

141 (52.8%)

  Leflunomide

0 (0.0%)

  Sulfasalazine

18 (6.7%)

  Oral glucocorticoids

17 (6.4%)

  Parenteral glucocorticoids

126 (47.2%)

  No RA medication

2 (0.7%)

Medication combinations prescribed

  No RA medication

2 (0.7%)

  MTX only

51 (19.1%)

  Other DMARDs only

20 (7.5%)

  Oral glucocorticoids only

2 (0.7%)

  Parenteral glucocorticoids only

15 (5.6%)

  MTX & other DMARDs

53 (19.9%)

  MTX & oral glucocorticoids

6 (2.2%)

  MTX & parenteral glucocorticoids

33 (12.4%)

  Other DMARDs & oral glucocorticoids

2 (0.7%)

  Other DMARDs & parenteral glucocorticoids

23 (8.6%)

  Oral & parenteral glucocorticoids

1 (0.4%)

  MTX, other DMARDs & oral glucocorticoids

5 (1.9%)

  MTX, other DMARDs & parenteral glucocorticoids

53 (19.9%)

  MTX, oral & parenteral glucocorticoids

1 (0.4%)

  1. Values are number (percentage) or mean (standard deviation). Abbreviations: BMI (Body Mass Index), SDAI (Simple disease activity index), DAS28-CRP (Disease Activity Score-28 for Rheumatoid Arthritis with C-Reactive Protein).