Table 2 Overview of software packages compliant with ASL-BIDS. An asterisk indicates extensive testing with 51 non-public, clinical datasets from a variety of ASL techniques.

ASLDRO³⁰

Open source tool to generate BIDS-compliant simulated ASL digital reference object data. Raw ASL time series comprising control, label and M0 volumes are synthesized from ground truth images according to configurable acquisition and labelling parameters.

https://github.com/gold-standard-phantoms/asldro

ASL-MRICloud³¹

Cloud based tool for processing ASL data. It supports processing of single and multi-PLD data and NIfTI input. JSON and ASL-BIDS are currently not supported.

https://braingps.mricloud.org

ASLPrep³²

ASL data preprocessing and cerebral blood flow computation pipeline, designed for easy accessibility, state-of-the art interface, and robustness to acquisition variations. BIDS and ASL-BIDS are supported.

https://aslprep.readthedocs.io/en/latest/index.html

ASLtoolbox^33,34

One of the first Matlab toolboxes for processing ASL data. It contains a graphical user interface and processes single and multi-PLD data. It accepts input in NIfTi, but does not support JSON or ASL-BIDS.

https://cfn.upenn.edu/zewang/ASLtbx.php

BASIL³⁵

Toolbox within the FMRIB Software Library providing the tools to analyze ASL datasets with quantification based on Bayesian inference principles. The toolbox accepts both single- and multi-PLD, and also Time-encoded and vessel-selective ASL data in NIfTI-format. Support for ASL-BIDS is in development.

https://asl-docs.readthedocs.io/en/latest/

*ExploreASL⁴

ExploreASL an SPM-based toolbox for processing, statistical analysis, and quality control of ASL datasets. ExploreASL fully supports ASL-BIDS input.

exploreasl.org; https://github.com/ExploreASL/ExploreASL