Table 1 Hepatotoxic and Cardiotoxic compounds.
From: Multi-omics HeCaToS dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds
Hepatotoxic compounds(abbreviation) | Drug class | Cardiotoxic compounds (abbreviation) | Drug class |
|---|---|---|---|
Fluorouracil (5FU) | antimetabolites | Fluorouracil (5FU) | Antimetabolites |
Acetaminophen (APAP) | analgesics and antipyretics | Doxorubicin (DOX) | Anthracyclines |
Azathioprine (AZA) | immunosuppressants | Epirubicin (EPI) | Anthracyclines |
Cyclosporin A (CYC) | immunosuppressants | Idarubicin (IDA) | Anthracyclines |
Diclofenac (DIC) | NSAIDs | Daunorubicin (DAU) | Anthracyclines |
Isoniazid (ISO) | antituberculosis agents | Amiodarone (AMI) | Antiarrhythmics |
Methotrexate (MTX) | antimetabolites | Celecoxib (CEL) | NSAIDs, COX-2 inhibitors |
Phenytoin (PHE) | anticonvulsants | Docetaxel (DOC) | Taxanes |
Rifampicin (RIF) | antimycobacterials | Mitoxantrone (MIT/MXT) | Anthracenediones |
Valproic acid (VPA) | anticonvulsants | Paclitaxel (PAC/PTX) | antimicrotubule agents |
