Fig. 4 | Scientific Data

Fig. 4

From: Identifying tumour microenvironment-related signature that correlates with prognosis and immunotherapy response in breast cancer

Fig. 4

The prognostic signature positively correlated with tumor mutation burden. (a) Box plot showing the correlation of TMB with risk score of the prognostic signature. Significance P values were calculated using Wilcoxon rank sum test. (b) Scatter plots depicting the spearman correlation between risk score of the prognostic signature and TMB. (c) The waterfall plot of tumor somatic mutation displayed distribution of top 20 highly mutated genes in the high-risk (left-panel) and low-risk (right-panel) score groups. (d) Significant enrichment of mutant genes in the high and low risk score groups. ***P < 0.001; **P < 0.01; *P < 0.05.

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