Fig. 2
Single-cell metabolic flux mapping reveals the heterogeneity of metabolism between cell types and diseases. (A,B) Profile of the predicted fluxome of 168 metabolic modules. On the y-axis, each row displays the flux of a particular metabolic module for all the cells under various group cell type conditions (shown on the x-axis). The color scale bar represents the size and direction of metabolic fluxes. (C) Volcano map revealing differences in enzyme expression in endothelial cells in different diseases. The vertical axis provides average log2FC values, and the horizontal axis presents the difference between proportions. The color of each dot represents the direction of change. Enzymes that differ significantly are highlighted on the figure, and coloured annotations are added to the metabolic modules that they participate in.
