Fig. 1

Experimental design and workflow. (a) Schematic diagram of the strain development process for the four S. clavuligerus strains, WT, C1, OR, and NL. (b) Biomass parameters measured as viscosity and OD, and CA production of the four S. clavuligerus strains. Sampling time points for RNA extraction is indicated by gray dashed lines. (c) Workflow of RNA-seq and data analysis.