Fig. 1 | Scientific Data

Fig. 1

From: Analysis of AlphaMissense data in different protein groups and structural context

Fig. 1

Distribution of AlphaMissense predictions in transmembrane (a) and soluble regions (b) of TM proteins. Transmembrane and soluble parts were determined for HTP entries with a confidence score higher than 85. Benign and pathogenic AlphaMissense predictions for SNVs present in ClinVar were collected and split into true and false categories for plotting. Ambiguous AlphaMissense predictions (6% and 7% for TM and soluble regions, respectively) were not included.

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