Fig. 3
From: The stroke outcome optimization project: Acute ischemic strokes from a comprehensive stroke center
Top Panel: Bitmap image generated by our validation scripts for a single participant (#23). This image shows axial, sagittal and coronal slices, as well as a rendered image, in standard MNI space. The lesion, located in the right caudate nucleus, is depicted in red. White matter hyperintensities (periventricular) are visible on the anterior boundary of the left and right ventricles. Users can inspect this bitmap can as part of the quality assurance process. In particular, the unified segmentation and normalization method we use develops a virtuous cycle between the spatial warping and the tissue segmentation that drives the brain extraction. Therefore, an accurate volume rendering (right panel) is consistent with a successful spatial warping to standard space. Middle Panel: Despite the variable differences in quality and resolution of each individual FLAIR scan (renderings for four representative individuals shown on the left side), all are normalized into a standard space, as seen by the rendering of the mean normalized FLAIR scan from all individuals (right side). Bottom Panel: Lesion incidence map (N = 1461) for the SOOP dataset. Hotter colors show regions with higher injury incidence.
