Fig. 7

Quantitative spatial analysis of the nucleus accumbens (Acb/ACB) and other ventral striatal regions across rat brain atlases. (a) Lateral view of the WHS rat brain atlas (WHSSD) NAc (NAc-sh, dark purple; NAc-c, light purple) and VSR-u (red), with magnified panel showing the spatial position and angle of three selected atlas plates (dashed lines) from rostral (a1), middle (a2) and caudal (a3) parts of The Rat Brain in Stereotaxic Coordinates (RBSC) Acb and LSS. The WHSSD cut to correspond with the three selected atlas plates from RBSC (a1’-a3’), showing the spatial correspondence of the Acb and LSS (black dashed line filled with a transparent white colour) with regions in the WHSSD. The WHSSD NAc and VSR-u is highlighted with white dashed line for comparison. The inset (a1”-a3”) show the LSS and the subdivisions of the Acb. (b) Lateral view of the WHSSD NAc and VSR-u, showing the spatial position and angle of the selected atlas plates (a1-a3, dashed lines) and the remaining RBSC atlas plates including Acb and LSS annotations (solid lines). The boxes (b1-b3) indicate the three rostro-caudal parts used for analysis of the quantitative spatial overlap of the RBSC Acb and LSS with regions in the WHSSD. The pie charts (b1’-b3’) show the proportion of the RBSC LSS and Acb subdivisions situated in regions of the WHSSD. (c,d) Selected atlas plates (c1-c3,c1’-c3’,c1”-c3”), spatial position (d1-d3) and pie charts (d1’-d3’) for the Brain Maps (BM) ACB and FS annotations in relation to WHSSD regions, as described for (a,b). e-f) Selected atlas plates (e1-e3,e1’-e3’,e1”-e3”), spatial position (f1-f3) and pie charts (f1’-f3’) for the RBSC IPAC complex annotation in relation to WHSSD regions, as described for (a,b). Note that the atlas plates from BM are registered with a mediolateral angle of 4 degrees, which in c1-c3 and d1-d3 gives an illusion of a dorsoventral angle in some atlas plates. Abbreviations: aca, anterior commissure, anterior limb; aca-p, anterior commissure, posterior limb; ACB, nucleus accumbens; AcbC, accumbens nucleus, core; AcbSh, accumbens nucleus, shell; Am-u, amygdaloid area, unspecified; BFR-u, basal forebrain region, unspecified; BM, Brain Maps; CPu, caudate putamen; CLA, claustrum; Endo, endopiriform nucleus; GPe-l, globus pallidus external, lateral part; LAcbSh, lateral accumbens shell; LSS, lateral stripe of striatum; NAc, nucleus accumbens; NAc-c, nucleus accumbens, core; NAc-sh, nucleus accumbens, shell; OB-u, olfactory bulb, unspecified; PIR3; piriform cortex, layer 3; RBSC, The Rat Brain in Stereotaxic Coordinates; Sep, septal region; VSR-u, ventral striatal region, unspecified; V-u, ventricular system, unspecified; VP, ventral pallidum; WHSSD, WHS rat brain atlas.