Table 6 Genes ranked by their degree in a subgraph generated from all the shortest paths between selected abnormal CNS phenotypes and CNS neoplasms.

From: Petagraph: A large-scale unifying knowledge graph framework for integrating biomolecular and biomedical data

Gene Symbol

Degree Count

TP53

65

VHL

61

FGFR1

61

NF1

60

PIK3CA

46

IDH1

41

PTEN

39

DICER1

33

NF2

32

SUFU

31

INSR

28

SLX4

28

PTPN11

27

SMARCB1

26

SDHA

25

RERE

23

TUBB

23

TSC1

22

TGFBR2

22

KRAS

21

  1. This table lists genes based on their connectivity within the subgraph, indicating their potential involvement in both CNS phenotypic abnormalities and brain cancers. Higher degree counts suggest a stronger association with both conditions, highlighting these genes as key nodes (hubs) in the network and potential targets for further research.
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