Table 7 Summary of Concept-to-Concept Relationships in the MSigDB dataset within Petagraph.

From: Petagraph: A large-scale unifying knowledge graph framework for integrating biomolecular and biomedical data

Relationship Type

MSigDB Dataset Source

chr_band_contains_gene

MSigDB C1

inverse_chr_band_contains_gene

MSigDB C1

pathway_associated_with_gene

MSigDB C2

inverse_pathway_associated_with_gene

MSigDB C2

targets_expression_of_gene

MSigDB C3

inverse_targets_expression_of_gene

MSigDB C3

has_marker_gene

MSigDB C8

inverse_has_marker_gene

MSigDB C8

has_signature_gene

MSigDB H

inverse_has_signature_gene

MSigDB H

  1. This table details the types of relationships introduced by the MSigDB v7.4 datasets, linking MSigDB Concept nodes to HGNC Concept nodes. Each relationship type corresponds to specific MSigDB subsets: C1 (positional gene sets), C2 (curated gene sets), C3 (regulatory target gene sets), C8 (cell type signature gene sets), and H (hallmark gene sets). The table lists both the direct and inverse relationships that contribute to the 2,598,060 Concept-to-Concept connections added to Petagraph.
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