Fig. 2

Study cohort characteristics. (a–c) Numbers and distributions of male and female donors across brain regions and age. (d) Distribution of donors by the most similar ancestry superpopulation predicted by QDA (AFR: African, AMR: Admixed American, EUR: European, SAS: South Asian). (e–g) Distribution of donors by age, source brain bank and Braak PD staging. (h) Spearman correlation coefficients among PD-related phenotypes. Harvard: NIH NeuroBiobank at the Harvard Brain Tissue Resource Center; MSSM: NIH NeuroBioBank at the Mount Sinai Brain Bank; Udall: University of Miami Udall Center of Excellence for Parkinson's Disease Research; UMiami: NIH NeuroBioBank at the University of Miami and University of Miami Brain Endowment Bank.