Table 2 Summary of availability of clinical metadata stratified by source brain bank.
From: A multi-region single nucleus transcriptomic atlas of Parkinson’s disease
Table Name | Description | Brain Bank | Ref [PMID] | |||
|---|---|---|---|---|---|---|
UD | HA | UM | MS | |||
PD Medical History | initiation and use of PD medication, changes of diagnosis over time, indication of surgeries | X | X | X | X | |
Family History PD | indication of PD diagnosis for father, mother and/or other relatives | X | X | |||
Smoking and alcohol history | indication and quantification of severity of smoking and alcohol consumption | X | X | X | ||
Epworth Sleepiness Scale | general level of daytime sleepiness | X | 1798888 | |||
LBD_Cohort_Clinical_Data | clinical symptoms (e.g. visual hallucionations, loss of memory, mood disorder) | X | X | X | X | |
LBD_Cohort_Path_Data | neuropathological assessments (CERADa, AD Braak, PD Braak) | X | X | X | X | |
MDS UPDRSb Part I | non-motor symptoms covering aspects like mood, cognition and sleep | X | 12815652 | |||
MDS UPDRSb Part II | motor symptoms impacting daily activities | X | X | 12815652 | ||
MDS UPDRSb Part IV | motor complications related to PD disease treatment | X | 12815652 | |||
MMSEc | screening for cognitive impairment and monitoring fo changes in mental status over time | X | X | 1202204 | ||
Modified Schwab & England (ADLd) | assessment of the capabilities of people with impaired mobility | X | ||||
UPDRSb | other UPDRS metrics not involved in Part I-IV | X | 12815652 | |||