Table 1 The effect size of metadata variables on gut microbial composition.
Taxonomic level | Factor | Sample size (HC, RA) | R2 (effect size) | P-value (Permutaion = 999) |
|---|---|---|---|---|
Phylum | Disease | 2038 (1086, 952) | 0.00246 | 0.007 |
Age | 2038 (1086, 952) | 0.07506 | 0.001 | |
Gender | 2038 (1086, 952) | 0.00096 | 0.119 | |
Disease (adj. age) | 2038 (1086, 952) | 0.07698 | 0.001 | |
Class | Disease | 2038 (1086, 952) | 0.00407 | 0.001 |
Age | 2038 (1086, 952) | 0.06352 | 0.001 | |
Gender | 2038 (1086, 952) | 0.00168 | 0.015 | |
Disease (adj. age&gender) | 2038 (1086, 952) | 0.06677 | 0.001 | |
Order | Disease | 2038 (1086, 952) | 0.00418 | 0.001 |
Age | 2038 (1086, 952) | 0.06333 | 0.001 | |
Gender | 2038 (1086, 952) | 0.0016 | 0.015 | |
Disease (adj. age&gender) | 2038 (1086, 952) | 0.06662 | 0.001 | |
Family | Disease | 2038 (1086, 952) | 0.00401 | 0.001 |
Age | 2038 (1086, 952) | 0.05714 | 0.001 | |
Gender | 2038 (1086, 952) | 0.00192 | 0.003 | |
Disease (adj. age&gender) | 2038 (1086, 952) | 0.0611 | 0.001 | |
Genus | Disease | 2038 (1086, 952) | 0.00829 | 0.001 |
Age | 2038 (1086, 952) | 0.0498 | 0.001 | |
Gender | 2038 (1086, 952) | 0.0018 | 0.001 | |
Disease (adj. age&gender) | 2038 (1086, 952) | 0.05702 | 0.001 | |
ASV | Disease | 2038 (1086, 952) | 0.00674 | 0.001 |
Age | 2038 (1086, 952) | 0.04491 | 0.001 | |
Gender | 2038 (1086, 952) | 0.00108 | 0.001 | |
Disease (adj. age&gender) | 2038 (1086, 952) | 0.05028 | 0.001 |
