Table 1 Cox proportional hazards regression analyses of KCNB1 expression and other characteristics in relation to overall survival in gliomas from the CGGA cohort.
From: Role of KCNB1 in the prognosis of gliomas and autophagy modulation
Clinical Characteristic | No. (%) | OS months (95% CI) | Univariate analysis | Multivariable analysis | ||
|---|---|---|---|---|---|---|
P | HR | 95%CI | P | |||
Age, years | Â | Â | 0.005 | Â | Â | 0.4 |
  ≤50 | 62 (50%) | 22.5–40.9 |  |  |  |  |
  >50 | 62 (50%) | 10.9–13.9 |  |  |  |  |
Gender | Â | Â | 0.297 | Â | Â | Â |
  Male | 79 (63.7%) | 4.9–24.1 |  |  |  |  |
  Female | 45 (36.3%) | 11.2–34.2 |  |  |  |  |
Chemotherapy |  |  | 0.002 | 0.43 | 0.26–0.72 | 0.001 |
  positive | 78 (62.9%) | 17.9–37.2 |  |  |  |  |
  negative | 32 (25.8%) | 7.9–11.4 |  |  |  |  |
  NA | 14 (11.3%) |  |  |  |  |  |
Radiotherapy | Â | Â | 0.07 | Â | Â | Â |
  positive | 91 (73.4%) | 10.2–35.0 |  |  |  |  |
  negative | 21 (16.9%) | 1.2–19.7 |  |  |  |  |
  NA | 12 (9.7%) |  |  |  |  |  |
KCNB1 |  |  | 0.001 | 0.45 | 0.25–0.80 | 0.007 |
  High expression | 62 (50%) | 15.8–40.0 |  |  |  |  |
  Low expression | 62 (50%) | 9.7–15.3 |  |  |  |  |
