Figure 2 | Scientific Reports

Figure 2

From: Identification of Mutant Genes and Introgressed Tiger Salamander DNA in the Laboratory Axolotl, Ambystoma mexicanum

Figure 2

Albino results from a mutation in tiger salamander tyr. (A) SNPs identified in the tyr 3′ UTR of WT axolotls, albino axolotls, and wild caught tiger salamanders. (B) FISH and genetic mapping localizes tyr to the distal tip of linkage group 7. M, megabases. (C) Genomic structure of tyr. Orange box, region deleted in tyr a. Black arrowheads, primer sites for identification of SNPs. Red arrowhead, site targeted for TALEN mutagenesis. (D) WT and TALEN-targeted tyr mosaic larva, phenocopying the albino mutant. Scale bar: 5 mm.

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