Figure 2 | Scientific Reports

Figure 2

From: Protectin DX increases survival in a mouse model of sepsis by ameliorating inflammation and modulating macrophage phenotype

Figure 2

PDX protected CLP mice from multiple-organ injury. Representative images of lung (magnification 200X), liver and kidney (magnification 400X) histology staining with hematoxylin and eosin. The normal lung (A), liver (E) and kidney (I) structure in sham group. CLP mice showed that lung (B), liver (F) and kidney (J) were all injured. PDX mitigated organ injury in septic mice (C,G and K). Organ injury scores in the three groups (D,H and L). The concentration of alanine aminotranferase (ALT) (M), aspartate amniotransferase (AST) (N), creatinine (Cr) (O) and blood urea nitrogen (BUN) (P) in blood was determined by using an automated chemistry analyzer. Data are presented as means ± SEM (n = 6). # P < 0.01.

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