Figure 3 | Scientific Reports

Figure 3

From: Protectin DX increases survival in a mouse model of sepsis by ameliorating inflammation and modulating macrophage phenotype

Figure 3

PDX enhanced bacterial clearance and increased the number of macrophage in peritoneum of CLP mice. Bacterial load in both of blood (A) and peritoneal lavage fluid (B) were decreased by PDX treatment in septic mice. Leukocytes including neutrophils, monocytes and macrophages, infiltrated to peritoneum in response to sepsis (C). PDX inhibited the neutrophils infiltration and promoted macrophages migrate to peritoneal cavity of CLP mice (C). Data are means ± SEM (n = 6). *P < 0.05, # P < 0.01.

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