Figure 7
From: The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling
The effects of ML204 on calcium influx in the podocytes. (a) The representative effect of acute applications of 20 µM ML204 followed by 10 µM Ang II on Ca2+ level in the podocytes (in calcium-containing media). (b) Representative effect of ML204 (20 µM, 10 min incubation) on Ca2+ transient evoked in the podocytes by 10 µM Ang II. (c) The representative effect of the acute application of 20 µM ML204 on Ca2+ level in the podocytes in calcium-free solution. (d) Graph summarizing the effects of Ang II on calcium influx in the podocytes in presence of ML204, or an acute application of ML204 alone. (i,j) noted on graph is number of animals (i) and podocytes (j) analyzed in each group. ns denotes no statistically significant difference versus Ang II application in the absence of the inhibitor.
