Figure 8
From: The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling
The involvement of TRPC6 channels into the Ang II–dependent calcium influx in the podocytes. (a) Representative effects of the TRPC channel blockers clemizole hydrochloride (Clem, 5 µM, 10 min) and SAR7334 (1 µM, 10 min) on Ca2+ transients evoked in the podocytes with 10 µM Ang II. (b) Graph summarizing the effects of Ang II on calcium influx in the podocytes in presence of clemizole and SAR7334. (i,j) noted on graph is number of animals (i) and podocytes (j) analyzed in each group. *P < 0.05 versus Ang II.
