Figure 5
From: Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

Fadrozole significantly suppressed high-salt-induced hypertension in hAS+/− mice. hAS+/− transgenic mice were fed with HS for 1 month and the BPs were measured. The mice on HS were treated continually with fadrozole for 2 months, the BPs of hAS+/− mice were tested at the end of 1 week and 2 months treatment of fadrozole respectively. **p < 0.01; ***p < 0.001.