Table 2 Plasma electrolytes and renin activity as well as urinary excreted electrolytes and pH in AS+/− and WT mice treated with NS and HS diets.

From: Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

Electrolytes

 

WT

AS+/−

Plasma

 Na+, mmol/L

NS

147 ± 0.51 (5)

151 ± 0.32 (15)

HS

148 ± 0.51 (5)

152 ± 0.69 (15)§

 K+, mmol/L

NS

4.8 ± 0.06 (5)

4.5 ± 0.07 (15)

HS

4.88 ± 0.08 (5)

4.0 ± 0.06 (15)*

 Renin activity

NS

5.19 ± 0.25 (4)

1.7 ± 0.31 (15)

HS

285 ± 43.73 (5)

208 ± 16.5 (15)§

Urine

 Na+, mmol/L

NS

125 ± 16.99 (5)

95 ± 8.17 (15)

HS

285 ± 43.73 (5)

208 ± 16.5 (15)§

 K+, mmol/L

NS

180 ± 20.46 (5)

134 ± 15.97 (15)

HS

62 ± 11.68 (5)

71 ± 7.16 (15)*

 PH

NS

7.0 (5)

6.9 (14)

HS

7.7 (5)#

7.0 (15)

  1. Values are means ± SE and numbers in parentheses represent numbers of used animals. *p < 0.05 HS versus NS in AS+/− groups, p<0.05, AS+/− versus WT with NS; § p<0.05, AS+/− versus WT with HS; # p < 0.05, HS versus NS in WTgroups.