Figure 1

Effects of Xiaoyaosan on anxiety-like behaviours. The EPM test, OFT, and NSF test were conducted at the end of the experiment. The percentage of entries and time spent in the open arms and the total distance travelled in the EPM were measured. The total distance travelled and percentage of time spent in open area of the OFT were determined. The latency of the rats to feed within 5 min in the NSF test were recorded. (A) The track maps of the rats in the different groups in the EPM test and OFT. (B) Percentage of entries in open arms of the EPM. (C) Percentage of time spent in the open arms of the EPM. (D) Total distance travelled in the EPM. (E) Total distance travelled in the OFT. (F) Percentage of time spent in the open area of the OFT. (G) Latency to feed in the NSF test. Values are presented as the means ± SEM with 9–10 rats in each group. *P < 0.05 or **P < 0.01 versus the control group. Δ P < 0.05 or ΔΔ P < 0.01 versus the vehicle (distilled water) group. # P < 0.05 or ## P < 0.01 versus the vehicle (dissolvent) group.