Figure 3 | Scientific Reports

Figure 3

From: Xiaoyaosan exerts anxiolytic-like effects by down-regulating the TNF-α/JAK2-STAT3 pathway in the rat hippocampus

Figure 3

Effects of Xiaoyaosan on the expression of the TNF-α, p-JAK2 and STAT3 proteins in the rat hippocampus. (A) Representative micrographs of immunohistochemical staining for the TNF-α, p-JAK2 and STAT3 proteins (scale bar = 50 μm, 400 × magnification) in the hippocampal DG region. (B) Quantitative analysis of the TNF-α protein levels. (C) Quantitative analysis of the p-JAK2 protein levels. (D) Quantitative analysis of the STAT3 protein levels. Values are presented as the means ± SEM from 5 rats in each group. **P < 0.01 versus the control group. Δ P < 0.05 or ΔΔ P < 0.01 versus the vehicle (distilled water) group. ## P < 0.01 versus the vehicle (dissolvent) group.

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