Figure 1 | Scientific Reports

Figure 1

From: Integrative analysis of multi-omics data reveals distinct impacts of DDB1-CUL4 associated factors in human lung adenocarcinomas

Figure 1

VPRBP, DTL, DCAF4, DCAF12 and DCAF13 are consistently deregulated in lung adenocarcinoma. VPRBP gene expression was significantly downregulated, whereas DTL, DCAF4, DCAF12 and DCAF13 were significantly upregulated in LuADCs (indicated in orange; GSE19188: N = 45; GSE31210: N = 226; GSE19804: N = 60) compared to expression in normal lung tissue (indicated in blue; GSE19188: N = 65; GSE31210: N = 20; GSE19804: N = 60). Increased or decreased gene expression cut-off: 2-fold and adjusted p < 0.05.

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