Figure 3 | Scientific Reports

Figure 3

From: Pharmacokinetic-Pharmacodynamic modelling of intracellular Mycobacterium tuberculosis growth and kill rates is predictive of clinical treatment duration

Figure 3

Intracellular (macrophage) and extracellular M. tuberculosis time-kill relationships. (a) Simulated concentration–kill rate relationship based on parameters generated from analysing intracellular Mtb kill curves for RIF (black circles), ETB (black triangles), INH (black diamonds) and PZA (black squares). (b) shows the concentration–kill relationship for RIF intracellular (black circles) and extracellular (open circles). (c) show the concentration–kill relationship of ETB intracellularly (black triangles) and extracellularly (open triangles) and (d) for the concentration–kill relationship of INH intracellularly (black diamonds) and extracellularly (open diamonds).

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