Figure 4
From: Identification of small molecule inhibitors of Interleukin-18
IFN-γ Secretion Assay with selected inhibitors. Human IL-18 bioassay for the detection of secreted IFN-γ using increasing concentrations of hIL-18. (A) Inhibition curves obtained with a constant 1 uM inhibitor concentration and a cell concentration of 1 × 106 cells ml−1. (B) Synergistic inhibition curves obtained by adding a final concentration of 1 uM total inhibitor of both compounds, cell concentration was 1 × 106 cells ml−1.
