Table 5 Clinicopathological characteristics of the patients included in the study.

From: Towards Personalized Medicine in Melanoma: Implementation of a Clinical Next-Generation Sequencing Panel

Variables

n = 100

Epidemiological features

 Age at diagnosis [median, (range)]

65.5 (21–90)

Age at diagnosis (%)

  <40

6

  40–65

44

  >65

50

Sex (%)

  Male

53

  Female

47

Clinical melanoma features

Anatomic site (%)

  Head/neck

16

  Upper extremities

16

  Trunk

42

  Lower extremities

18

  Acral

8

Sun related site (%)

  Non exposed

21

  Occasionally exposed

63

  Usually exposed

16

Pathological melanoma features

Histological subtype (%)

  LMM

10

  SSM

68

  NM

14

  AML

8

Breslow thickness (mean (±SD))

1.9 ± 2.1

Breslow thickness (%)

  <1 mm

47

  1–2 mm

21

  2–4 mm

19

  >4 mm

13

Ulceration (%)

  No

74

  Yes

26

Regression (%)

  No

52

  <50%

41

  >50%

7

Mitoses/mm2 (%)

  <1

48

  >1

52

Growth rate (%)

  SGM

76

  FGM

24

Tumor stage (%)

  Localized (I–II)

75

  Locoregional and metastatic disease (III–IV)

25

Months follow-up [median, (range)]

32 (6–121)

Clinical outcome (%)

  Stable disease

81

  Relapse (locoregional vs distant metastasis)

8

  Exitus

11