Figure 4 | Scientific Reports

Figure 4

From: TRPV1 temperature activation is specifically sensitive to strong decreases in amino acid hydrophobicity

Figure 4

Hydropathy changes induced by mutations. (a) Histograms showing the change in hydropathy (hydropathymutant − hydropathyWT) for mutations in ‘functional’ clones screened with temperature or capsaicin. Data is normalized so that the sum of a bin from the ‘functional’ group and the respective bin from the ‘less functional’ group is equal to 100%. (b) Change in hydropathy for all 1,110 temperature- and 1,145 capsaicin-characterized mutations.

Back to article page