Table 1 Melting temperatures of RNA G4 oligos annealed in 100 mM KCl, 20 mM Tris-HCl, pH 7.5.
From: Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression
RNA G4 oligos | T m (°C)a | |
---|---|---|
BCL2 | wt | 78 ± 2.1 |
mut | 64 ± 0.2 | |
Long BCL2 b | wt | 74.5 ± 3.5 |
mut | 58 ± 2 | |
CXCL14 | wt | >90c |
mut | 73 ± 0.5 | |
TAOK2 | wt | 68 ± 0.5 |
mut | 75 ± 1 |