Figure 2

ETO-curcumin exerts superior anti-inflammatory effects compared to standard curcumin on DSS-induced inflammation at 50 mg/kg body weight. (A) Graphical representation of curcumin treatment strategy. (B) Changes in individual categories of disease activity index (DAI) (top), body weight changes, stool consistency and stool bleeding (left-right). Changes in DAI (bottom). (C) Representative image of colons (left) and average colon length (right). (D) Spleen weight and (E) Histology score on day 14. (F) Representative haematoxylin and easin (H&E) staining of large intestine on day 14. 100x magnification (left) and 400x magnification (right). *p < 0.05, **p < 0.01, ***p < 0.001.