Table 2 Statistical calculations for high IGF-1/low miR-181 status.

From: Identification of IGF-1-enhanced cytokine expressions targeted by miR-181d in glioblastomas via an integrative miRNA/mRNA regulatory network analysis

Covariate

Hazard Ratio

95% Conf-U

95% Conf-L

stdErr

p. value

High IGF1/Low miR-181d

1.435

1.956

1.053

0.158

0.022

G-CIMP

3.876

7.547

1.991

0.34

<0.001

Age > 60

1.433

1.942

1.058

0.155

0.02

Karnofsky score ≥ 80

1.988

2.807

1.408

0.176

<0.001

Gender (male)

1.061

1.446

0.778

0.158

0.708

  1. IGF1-miR-181 status is a strong and independently significant prognostic factor among Karnofsky performance status, age, gender and CIMP status. stdErr: stander error; Conf-L/U: Confidence interval lower limit/upper limit.