Table 1 Immunophenotypic marker profiles of the original patient leukemia cells, CHH-1 cells and the tumor formed by CHH-1 cells.

From: Establishment of a novel human lymphoblastic cell strain with the long arm of chromosome 11 aberration without MLL rearrangement

 

Patient

CHH-1

Tumor

 

Patient

CHH-1

Tumor

CD34

79.93%

53.40%

−

CD13

−

−

−

TdT

89.12%

98.80%

+

CD14

−

−

N

HLA-DR

90.60%

100.00%

N

CD15

−

−

N

CD10

87.16%

67.50%

−

CD1α

−

−

−

CD19

87.35%

81.80%

+

CD16

−

−

N

CD79α

90.10%

99.00%

+

CD4

−

N

−

CD20

67.36%

94.40%

+

CD8

−

N

−

CD38

86.00%

99.80%

+

CD22

N

99.60%

+

cyIgM

−

−

N

CD23

N

92.40%

+

CD3

−

−

−

Kappa

N

−

−

CD2

−

−

N

Lammda

N

−

−

CD5

−

−

−

c-myc

N

N

+

CD7

−

−

N

Bcl-2

N

N

+

CD138

−

−

−

Bcl-6

N

N

−

CD56

−

−

+

CD123

N

N

−

CD64

−

−

N

CyclinD1

N

N

−

MPO

−

−

−

S100

N

N

−

CD117

−

−

N

SOX11

N

N

−

CD33

−

−

N

Ki-67

N

N

>90%

CD11c

−

−

N

    
  1. For the original patient leukemia cells and CHH-1 cells, the values shown are the means of percent positive cells in three tests analyzed by flow cytometry. For the tumor formed by CHH-1 cells, the qualitative results are detected by immunohistochemistry. CD: cluster of differentiation; MPO: myeloperoxidase; TdT: terminal deoxynucleotidyl transferase; HLA: human leukocyte antigen; cy: cytoplasmic expression; N: not tested.