Figure 7

The treatment effects on plasma enzymes, blood cells count and haematological parameters of mice. (A–D) Effects of APW alone, the combination of cisplatin and 5-FU and the combination of APW, cisplatin and 5-FU treatments on the levels of plasma enzymes AST, ALT, LDH and CK in EC-109 intraperitoneal xenograft-bearing nude mice after 20 days of treatment. Data are expressed as the mean + S.E.M. of 10–13 samples. ^* p < 0.05, ^*** p < 0.001 as compared with naïve; ^# p < 0.05 as compared with control by one-way ANOVA followed by post-hoc Tukey’s multiple comparison test. (E–I) Effects of APW alone, the combination of cisplatin and 5-FU and the combination of APW, cisplatin and 5-FU treatments on blood cells count and haematological parameters of mice. Results were expressed as mean + S.E.M. of 5 mice each group. *p < 0.05, **p < 0.01, ***p < 0.001 when treatment groups compared with control group. ^# p < 0.05, ^## p < 0.01, ^### p < 0.001 as compared among treatment groups by one-way ANOVA followed by post-hoc Tukey’s multiple comparison test.