Figure 4 | Scientific Reports

Figure 4

From: Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in mice

Figure 4

Changes of mTORC2 related signaling in TSC1 tg mice. (a) Phosphorylation of ATK at serine 473 and (b) Phosphorylation of PCKα at serine 657 in the heart, liver and skeletal muscle (SKM). (c) Phosphorylation of GSK3β at serine 9 in liver and heart. The protein band intensity was normalized to wild type mice in each group. The asterisks indicate statistical significance between Tsc1 tg and wild type mice (*p < 0.05, n = 6 for each group, includes both male and female mice).

Back to article page