Figure 5 | Scientific Reports

Figure 5

From: As a carrier–transporter for hair follicle reconstitution, platelet-rich plasma promotes proliferation and induction of mouse dermal papilla cells

Figure 5

In vivo hair follicle reconstitution. The results of the mini-chamber assay showed that the positive control induced hair follicles (a), and the negative control did not (b), DPCs cultured in general medium induced sparse hair follicles (c). DPCs treated with 5% PRP induced more hair follicles (d). Corresponding haematoxylin and eosin-stained sections of each groups (e–h). Scale bars = 200 μm. The number of hairs induced by DPCs treated with 5% PRP was significantly higher than that induced by DPCs treated with culture medium alone (i). *P < 0.05 vs. Control. Cultured human DPCs engrafted with freshly isolated neonatal foreskin epidermal cells, no hair induction was observed by gross (j), and no hair follicle was observed within the skin of nude mice by histological examination (k).

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