Figure 3 | Scientific Reports

Figure 3

From: Detection of red blood cell surface antigens by probe-triggered cell collision and flow retardation in an autonomous microfluidic system

Figure 3

Attached cells in the trapping region perturb the motion of moving cells and force them perpendicular directions to the flow. Routs of moving RBC’s were analysed in the capture region in case of two different bound cell density (right and left panel). (a) Two microscopic pictures about the capillary taken in delayed time points (pink and light blue colours) were overlaid to visualize the attached cells (dark blue). Field of vision was divided to four equal regions those were analysed separately, the 2–4 regions were functionalized as indicated. (b) Positions of bound cells were indicated by black dots for better visualization. (c) Trajectories of 30–30 moving RBC’s were analysed. (d) Graph shows the SD of movement of cells in perpendicular direction to the flow of blood. Friedman and Dunn’s statistical tests were applied to reveal significant differences (*p < 0.05; **p < 0.01; ***p < 0.001, n = 30).

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