Table 2 Leiomyoma characteristics and results of the generalised estimating equations model including leiomyoma size, location and histotype (n = 683).

From: Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas

Leiomyoma characteristics

All leiomyomas (N = 763)

MED12-mutation-positive (n = 599)

MED12-mutation-negative (n = 164)

Multivariable-adjusted regression coefficient [95% CI]

P

Size (cm)1

3.0 (2.0–5.0)

3.0 (1.7–4.0)

4.0 (2.2–7.0)

−0.18 [−0.24, −0.12]

4.2 × 10 −9

Histopathological variant

24 (3.3)

10 (1.7)

14 (8.5)

−1.60 [−2.58, −0.63]

0.0013

Location2

 intramural

559 (73.2)

419 (69.9)

140 (85.4)

reference

1

 subserous

88 (11.6)

80 (13.4)

8 (4.9)

0.82 [0.34, 1.30]

0.00082

 submucous

44 (5.8)

38 (6.3)

6 (3.7)

0.52 [−0.12, 1.16]

0.11

  1. Data are median (inter quartile range) or n (%) unless otherwise specified. To adjust for multiple comparisons, P < 0.00147 indicated statistical significance (the Bonferroni correction). CI = confidence interval. 115 missing values: 13 mutation-positive and 2 –negative. 272 missing values: 62 mutation-positive and 10 –negative.
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