Figure 7 | Scientific Reports

Figure 7

From: Translation, but not transfection limits clinically relevant, exogenous mRNA based induction of alpha-4 integrin expression on human mesenchymal stem cells

Figure 7

ITGA4 protein distribution in (ARCA)-ITGA4-mRNA transfected MSCs. Time-course of ITGA4 protein production – note its translocation from perinuclear area in 3 and 5 hour time-points toward the cell membrane in 8 and 24 hour time points (A). The presence of ITGA4 protein on the cell membrane was confirmed in living cells by flow cytometry performed 20 h after transfection (B). red – ITGA4 protein, blue – Hoechst 33258. Scale bar: 20 µm.

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