Table 1 Classification of 144 selected studies according to primary research objectives and methodological design.

From: Leukemia and Risk of Venous Thromboembolism: A Meta-analysis and Systematic Review of 144 Studies Comprising 162,126 Patients

Class of study

No. of studies

No. of cohorts

Patients

Events

Incidence of VTE (95% CI)

A

75

87

9,061

448

0.05 (0.04, 0.06)

B

40

41

2,431

108

0.06 (0.04, 0.08)

C

20

21

5,308

263

0.04 (0.03, 0.05)

D

7

7

308

23

0.06 (0.02, 0.14)

E

72

71

153,062

2,770

0.03 (0.03, 0.04)

  1. A indicates all prospective studies comprising B, C, D. B indicates prospective studies evaluating the outcomes of clinical therapeutic protocols describing VTE as a complication. C indicates prospective studies investigating the prevalence of clinical venous thrombotic events. D indicates prospective studies evaluating laboratory parameters of hypercoagulability thatdescribe clinical thrombotic complications as additional information. E indicates retrospective studies.
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