Table 3 Top and bottom five differentially expressed genes.

From: RNA-Seq based genome-wide analysis reveals loss of inter-chromosomal regulation in breast cancer

Gene Symbol

Log2FC

p-value

False Discovery Rate

References In Breast Cancer

COL11A1

5.069

1.77 × 10−212

4.59 × 10−210

21,22,23

MMP11

4.147

1.14 × 10−223

4.59 × 10−231

67,68,69

KIF4A

3.905

0

0

70,71,72

GRM8

3.559

3.36 × 10−133

2.52 × 10−131

73

TPX2

3.284

1.07 × 10−313

5.45 × 10−310

74, 75

\(\vdots \)

\(\vdots \)

\(\vdots \)

\(\vdots \)

\(\vdots \)

PI16

−4.651

3.86 × 10−117

2.31 × 10−115

 

CPA1

−4.868

5.19 × 10−122

3.35 × 10−120

76

FIGF

−5.165

2.24 × 10−198

4.51 × 10−196

27

ADH1B

−5.697

5.58 × 10−144

4.74 × 10−142

 

CA4

−6.431

2.3 × 10−192

4.4 × 10−190

 
  1. Linear model raw p-values results were corrected for multiple comparisons using the False Discovery Rate method. Gene expression differences between cancerous and healthy samples are presented in log 2 scale (log 2 FC).