Table 4 Top five increased and decreased functions.

From: RNA-Seq based genome-wide analysis reveals loss of inter-chromosomal regulation in breast cancer

Annotated Functions

p-value

Activation Z-score

# Molecules

G2 phase

6.66 × 10−05

2.19

30

G2/M phase

1.31 × 10−03

2.186

23

Inflammation of organ

3.39 × 10−04

1.951

49

Synthesis of progesterone

1.47 × 10−02

1.399

7

Binding of endothelial cells

2.92 × 10−03

1.35

20

\(\vdots \)

\(\vdots \)

\(\vdots \)

\(\vdots \)

Vasculogenesis

1.74 × 10−09

−3.115

101

Angiogenesis

7.38 × 10−10

−3.176

103

Growth of epithelial tissue

4.12 × 10−10

−3.347

106

Migration of cells

1.08 × 10−14

−3.361

239

Differentiation of cells

2.40 × 10−05

−3.738

163

  1. Note that the annotated functions are ordered using the activation Z-score. Companion p-values and the number (#) of molecules present in each function are also included.